Yoshie Murakami

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BACKGROUND Adjustment disorders and major depression are common psychiatric disorders in patients with cancer and have a serious impact on quality of life. The problem in clinical oncology settings is underrecognition of these disorders; as a result, screening is recommended to detect them. The goal of the current study was to develop a new, brief screening(More)
The genetic diversity and the relationships among a collection of mustard (B. juncea) germplasm, including 41 accessions collected from Pakistan, 6 oilseed cultivars/ lines and 5 Japanese vegetable cultivars, were evaluated using random amplified polymorphic DNA (RAPD) markers. A total of 198 polymorphic amplified products were obtained from 30 decamer(More)
BACKGROUND To the authors' knowledge, there have been few studies of the psychologic distress after disclosure of genetic test results for hereditary nonpolyposis colorectal carcinoma (HNPCC). The objectives of this study were to identify the prevalence rates and predictors of psychologic distress and to evaluate the feelings of guilt after disclosure of(More)
An investigation was conducted to determine the extent of diversity and relationships among the Brassica juncea germplasm from Pakistan using morphological characters. A total of 52 accessions, including the collected germplasm as well as commercial cultivars/improved lines, were studied under field conditions at Tsukuba, Japan during 1995 and 1996. All the(More)
Genetic diversity of 30 radish (Raphanus sativus L.) accessions was investigated at the phenotypic level with morphological characters and at the DNA level using the random amplified polymorphic DNA (RAPD) technique. Thirty-six morpho-physiological traits were recorded from seedling stage to harvest. The 31 primers used generated 202 RAPD bands, of which(More)
BACKGROUND We assembled needed data on the prevalence and characteristics of BRCA1/2 in Japan. MATERIALS AND METHODS Our study of BRCA1/2 collected data at eight institutions in Japan on 320 individuals with a strong family history of breast cancer, according to the NCCN guidelines, by the end of March 2012. RESULTS Among 260 proband cases, 46 (17.7 %)(More)
Hyssopus officinalis transformed roots were induced by infection with Agrobacterium rhizogenes. The transformed roots grew well in hormone-free Woody Plant liquid medium producing high levels of phenolic compounds such as rosmarinic acid (maximum: 8.03% of dry weight) and lithospermic acid B (maximum: 3.89% of dry weight).
Stochastic switching is considered as a cost-saving strategy for adaptation to environmental challenges. We show here that stochastic switching of a monostable circuit can mediate the adaptation of the engineered OSU12-hisC Escherichia coli strain to histidine starvation. In this strain, the hisC gene was deleted from the His operon and placed under the(More)
Cell growth rate reflects an organism’s physiological state and largely relies on the ability of gene expression to respond to the environment. The relationship between cellular growth rate and gene expression remains unknown. Growth rate-coordinated changes in gene expression were discovered by analyzing exponentially growing Escherichia coli cells(More)
Gene rewiring is a common evolutionary phenomenon in nature that may lead to extinction for living organisms. Recent studies on synthetic biology demonstrate that cells can survive genetic rewiring. This survival (adaptation) is often linked to the stochastic expression of rewired genes with random transcriptional changes. However, the probability of(More)