Yoshiaki Seki

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AZT (3'-azido-3'-deoxythymidine; zidovudine), which is used for the prevention of mother-to-child transmission of HIV-1, is transplacentally transferred to the fetus across the blood-placenta barrier, which is composed of syncytiotrophoblasts. We recently showed that apical uptake of AZT by syncytiotrophoblasts is mediated by saturable transport system(s)(More)
The purpose of this study contributes to safe improvement in consideration of security in addition to convenience by the social media utilization in the company. The company uses the marketing using social media, but a lot of risks exist. We contribute to safe improvement by performing an example investigation in this study, and doing risk assessment. In(More)
ICT systems have been investigated for achieving flexible systems configuration, systems operation cost reduction, environmental impact reduction, etc. Cloud computing has attracted attention as technology that solves these. In the U.S., business cloud services, such as Amazon EC2/S3, Google Apps, Force.com, and Windows Azure, are gaining more and more(More)
The purpose of this study is to make social media utilization by enterprises safer, more secure, and more convenient. Enterprises use social media for marketing, but this presents a lot of risks. These risks were comprehensively extracted in our previous study, but it was only a qualitative study, so a quantitative evaluation is needed to make the risks'(More)
A possible approach to improve antiretroviral therapy with nucleoside reverse transcriptase inhibitors is to enhance inhibitor delivery to CD4-positive T cells. We previously showed that dehydroepiandrosterone sulfate (DHEAS) enhances zidovudine (AZT) transfer into syncytiotrophoblast. Here, we investigated whether DHEAS also enhances AZT transfer into a(More)
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