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- Publications
- Influence
Nitric oxide confers cisplatin resistance in human lung cancer cells through upregulation of aldo-keto reductase 1B10 and proteasome
- T. Matsunaga, Y. Yamaji, +10 authors A. Hara
- Biology, Medicine
- Free radical research
- 26 August 2014
Abstract In this study, we show that exposure of human lung cancer A549 cells to cisplatin (cis-diamminedichloroplatinum, CDDP) promotes production of nitric oxide (NO) through generation of reactive… Expand
PtdIns4KIIα generates endosomal PtdIns(4)P and is required for receptor sorting at early endosomes
- Yuji Henmi, Y. Morikawa, +5 authors K. Tanabe
- Biology, Medicine
- Molecular biology of the cell
- 15 March 2016
PtdIns4KIIα has been implicated in the regulation of endosomal traffic, but the role of its enzymatic activity and the site of its action have not been elucidated. Depletion of PtdIns4KIIα… Expand