Share This Author
Identification of ACA‐28, a 1′‐acetoxychavicol acetate analogue compound, as a novel modulator of ERK MAPK signaling, which preferentially kills human melanoma cells
ACA‐28, a synthetic derivative of 1′‐acetoxychavicol acetate (ACA), which is a natural ginger compound, effectively inhibited the growth of melanoma cancer cells wherein ERK MAPK signaling is hyperactivated due to mutations in the upstream activating regulators.
Melanogenesis Inhibitory Activity of Diterpenoid and Triterpenoid Constituents from the Aerial Part of Isodon trichocarpus
A methanol extract from the aerial part of Isodon trichocarpus (Labiatae) demonstrated inhibitory effects on melanogenesis in theophylline-stimulated murine B16 melanoma 4A5 cells, which could be the mechanism of melanogenesis inhibitory activity.
Melanogenesis inhibitory activity of a 7-O-9'-linked neolignan from Alpinia galanga fruit.
Labdane-Type Diterpenes, Galangalditerpenes A–C, with Melanogenesis Inhibitory Activity from the Fruit of Alpinia galanga
The melanogenesis inhibitory activities in theophylline-stimulated murine B16 melanoma 4A5 cells of these isolates, including the new diterpenes, were found to be more than 6–87-fold higher than that of arbutin, a commercially available positive control.
Acetoxybenzhydrols as highly active and stable analogues of 1'S-1'-acetoxychavicol, a potent antiallergic principal from Alpinia galanga.
Oryza Ceramide®, a rice-derived extract consisting of glucosylceramides and β-sitosterol glucoside, improves facial skin dehydration in Japanese subjects
Oryza Ceramide® improved facial TEWL, lip moisture, and visible pores, and these effects may be attributed to increases in epidermal ceramides, and the combination of rice GlcCer and BSG appears to be beneficial for improving facial skin conditions.
Acylated iridoid glycosides with hyaluronidase inhibitory activity from the rhizomes of Picrorhiza kurroa Royle ex Benth.
Geranylated Coumarins From Thai Medicinal Plant Mammea siamensis With Testosterone 5α-Reductase Inhibitory Activity
Geranylated coumarin constituents, kayeassamin I and mammeasins E and F, were newly isolated from the methanol extract of the flowers of Mammea siamensis and were found to inhibit testosterone 5α-reductase.
Collagen synthesis-promoting and collagenase inhibitory activities of constituents isolated from the rhizomes of Picrorhiza kurroa Royle ex Benth.
Two new aromatic glycosides, elengiosides A and B, from the flowers of Mimusops elengi
Two new aromatic glycosides, elengiosides A (1) and B (2), were isolated from the methanolic extract of the flowers of Mimusops elengi (Sapotaceae) together with 26 known compounds. Their…