Yoshiaki Kumamoto

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In vivo microdialysis was employed to measure the extracellular concentrations of dopamine (DA) in the medial preoptic area (MPOA) of rats during male sexual activity to look for a correlation with sexual activity. During copulation, the concentration of DA in the MPOA was significantly increased. A significant difference was detected in changes of DA(More)
The effects of long-term psychological stress on sexual behavior and brain catecholamines were investigated in rats. Stress was applied using the communication box developed by Ogawa and Kuwabara (1996), and a psychological stress group (n = 12), a physical stress group (n = 5), and a control group (n = 5) were established. Stress was applied for 1 hour(More)
It is reported that some elderly males exhibit both hypospermatogenesis and intratesticular arterial changes. These arterial changes are thought to contribute to spermatogenic damage. In this study the process of the damage to spermatogenesis induced by such changes was evaluated using stroke-prone spontaneously hypertensive rats (SHRSP). SHRSP showed a(More)
We report a case of adenocarcinoma arising in the ileal segment of an ileocystoplasty which had remained defunctionalized for 22 years, after conversion to the ileal conduit. In our case, inflammation or previous radiation as well as urine exposure are suggested to have participated in the development of the carcinoma in the augmented bladder.
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited To the Editor Chlamydia trachomatis (CT) infection in pregnancy can cause maternal disease, adverse pregnancy outcomes, and neonatal(More)
We investigated spermatogenic damage induced by anti-cancer agents in previous studies. The results showed that the damage to spermatogenesis induced by anti-cancer agents could be due to not only direct damaging effects on DNA synthesis but also a direct effect on Sertoli cell function. Thus, stimulating Sertoli cell function could protect against the(More)
Nocturnal LH pulse was analyzed in 4 prepubertal, 3 early pubertal and 2 midpubertal boys by measuring serum LH concentrations. Blood samples were taken every 30 minutes while awake, and every 20 minutes after subjects had gone to sleep. Serum LH was measured by using immunofluorometric assay (IFMA) with a lower detection limit of 0.02mIU/ml. Pulsatile LH(More)
We studied the actual general state of sexual dysfunction in 201 male diabetics (age range: 22-76 years) who were commuting outpatients, using the Sapporo Medical University's Sexual Function Questionnaire. The control group consisted of 6,426 healthy male subjects. The principal parameters taken into account by the Questionnaire were the libido and ability(More)
As you know, for penile erection, a sufficient amount of testosterone-induced nitric oxide is needed in the smooth muscle of the penile arterial wall. With aging, LOH syndrome and so on, the serum testosterone level decreases, resulting in a decline of penile erectile function. Furthermore, it is known that the enzyme PDE5 in the penile artery wall also(More)