Yoshiaki Kaji

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BACKGROUND The biological rhythm in comorbidity of depression and Parkinson disease (PD) is still unclear. For early diagnosis or clarification of the pathologic condition of comorbidity of depression and PD, the present study investigated the presence of circadian rhythm abnormalities in patients with depression. METHODS We measured the rectal(More)
Parkinson's disease (PD) is accompanied by nonmotor symptoms (NMS) such as mood disorders. Among them, depression and anxiety complicate PD and are present at high rates in PD patients. Organic depression is generally known to affect a patient's recovery from the sequelae of the primary disease; thus early detection and appropriate treatment are essential.(More)
Depression, apathy, and anhedonia are often comorbid in patients with Parkinson's disease. Since the morbid states of apathy and anhedonia are complicated, these symptoms are often difficult to diagnose. Several therapeutic methods for apathy and anhedonia are considered effective. However, the validity of these methods has not been established. Similar to(More)
Post-stroke depression (PSD) has an important impact on the quality of life of patients with stroke. We studied 100 stroke patients (mean age+/-SD: 64.6+/-11.6, range: 32-85 years) in the subacute phase (2-5 weeks after onset) and investigated the prevalence and clinical correlates of PSD in the subacute phase. The prevalences of PSD and major depression in(More)
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