Yoshiaki Ichibe

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Two patients with migraine and repetitive visual field defects of homonymous hemianopic type are reported. The visual field defects were confirmed by Goldmann perimetry and automated static perimetry. Neither computed tomography nor magnetic resonance imaging showed abnormal findings. Decreased cerebral blood flow at the left basal ganglion area was the(More)
Twenty five patients with optic neuritis (ON) of unknown etiology were treated with a high dosage of intravenous vitamin C. We measured blood levels of vitamin A, B1, B2, B6, B12, C, E, folate and zinc. All levels were compared with the normal values of our laboratory. The blood level of vitamin C (p < 0.001) was significantly less than the mean value of(More)
PURPOSE To evaluate the effect of motion stimulation without changing binocular disparity on stereopsis in strabismic patients. METHODS Static and moving stereopsis were measured in 120 normal children and 30 strabismic patients (9 esotropia, 14 exotropia, 7 intermittent exotropia). Using a portable game device (PSP; SONY, Japan), we created stereoscopic(More)
A bibliographic search was conducted of cases of Candida endophthalmitis reported in Japan and overseas between 2000 and 2011, in the Japana Centra Revuo Medicina Website of Japan Medical Abstracts Society (domestic reports) and MEDLINE (overseas reports). The investigation yielded 42 reports in domestic journals (49 cases ; hereinafter referred to as(More)
PURPOSE To investigate the etiology of bilateral disc swelling in Japanese. METHODS Using Kitasato University's Department of Neuro-Ophthalmology medical records and fundus photographs of the period December 1977 through November 2010, we retrospectively identified 121 outpatients who had been initially confirmed with bilateral disc swelling. RESULTS(More)
This paper examines the possibility of detecting 2 conditions which cause vision to deteriorate: Aged-Related Macular Degeneration (AMD), and the effects of aging on eyes using the features of PLR waveforms. These features were extracted using Fourier descriptors of PLR waveform shapes, weighted amplitudes of the waveforms, and a balanced combination of(More)
Haruki Abe Toshiaki Abe Shiro Amano Hiroyuki Arai Makoto Araie Kaoru Araki-Sasaki Shinsuke Ataka Masahiko Ayaki Noriyuki Azuma Jyorti Biswas (India) Dean Cestari (USA) Soon Phaik Chee (Singapore) Tai-ichiro Chikama Makoto Chikuda Shinki Chin Hideki Chuman Nobuyuki Ebihara Hiroshi Eguchi Takashi Fujikado Naoya Fujimoto Yujiro Fujino Takeo Fukuchi Masahiko(More)
BACKGROUND The waveforms of the pupillary light reflex (PLR) can be analyzed in a diagnostic test that allows for differentiation between disorders affecting photoreceptors and disorders affecting retinal ganglion cells, using various signal processing techniques. This procedure has been used on both healthy subjects and patients with age-related macular(More)
Leber's hereditary optic neuropathy(LHON) is a maternally inherited mitochondrial disease of an acute or subacute bilateral loss of central vision. G to A substitutions at nucleotide position 11778 in mitochondrial DNA(mt DNA) have been identified in approximately 40% to 90% of patients. In this study, regions containing mt DNA 11778 mutations were analyzed(More)
This article reviews the literature on point mutation of mitochondrial DNA (mtDNA) among Japanese and the authors' research data on pupil reaction in patients with Leber's hereditary optic neuropathy (LHON). Among Japanese, a higher frequency (80-90%) of point mutation at nucleotide position 11778 of mtDNA was found; other point mutations found were at(More)
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