Yoshiaki Fujita

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Diabetic polyneuropathy is a major complication of diabetes and the most common cause of peripheral neuropathy. Sensory-dominant neuropathy is the most common type. We previously used streptozotocin (STZ)-induced diabetic ddY mice with sensory neuropathy to evaluate the therapeutic effects of vascular endothelial growth factor and placental growth factor(More)
A new approach to the deformation modeling of vis-coehwtic objects for their shape control is presented. Manipulative operations of viscoeiastic objects can be found in many industrial fields such as food indust~ and medical product industry. Automatic operations of viscoelastic objects are eagerly requirwd in these jields. Since viscoelastic objects deform(More)
We examined the influence of castration on the volumes of sexually dimorphic nuclei, the amygdala pars medialis (Am) and lateralis (Al), and the anterior part of the preoptic nucleus, and on the immunoreactivity of luteinizing hormone-releasing hormone (LH-RH) in brains of Japanese toads captured in spring and autumn. Animals were castrated (GnX) and half(More)
Manipulative operations of rheological objects can be found in many industrial fields such as food industry and medical product industry. Automatic operations of rheological objects are eagerly required in these fields. In this paper, deformation transition graphs are proposed for the forming operations of theological objects. First, a novel forming machine(More)
Placental growth factor-2 (PlGF-2) exhibits neurotrophic activity in dorsal root ganglion (DRG) neurons through the neuropilin-1 (NP-1) receptor in vitro. To examine the potential utility of PlGF-2 therapy for treating diabetic neuropathy, we performed intramuscular PlGF-2 gene transfer by electroporation, and examined its effects on sensory neuropathy in(More)
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