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PURPOSE Systemic polyunsaturated fatty acids (PUFAs) were shown to improve the symptoms of dry eye syndrome due to their anti-inflammatory effects. This study evaluated the in vitro anti-inflammatory effects of PUFAs on human corneal epithelial (HCE) cells. METHODS HCE cells were incubated for 2 hours with different concentrations of PUFAs:(More)
The effect of high oxygen pressure on neural function was studied in the isolated nervous system of the cockroach. Intracellular and extracellular action potentials were recorded from single giant axons during exposure to 7 ATA (atmosphere absolute) (1 ATA = 0.1 MPa) of oxygen. Axonal excitability was measured as changes in stimulus strength-duration(More)
Human divers exposed to hyperbaric pressure may suffer from cognitive and motor impairments thought to be related to high pressure effects per ce. These effects, termed high pressure neurological syndrome (HPNS), appear at pressure above 1.1 MPa. HPNS involves CNS hyperexcitability that is partially attributed to augmented responses of the glutamatergic(More)
BACKGROUND Patients with type 2 diabetes mellitus (DM) display a predisposition for vascular disease. Platelets taken from vasculopathic diabetic patients, show enhanced stimuli-induced activation and aggregation responses. Aspirin remains the cornerstone antiplatelet agent for secondary prevention of vascular complications among diabetic patients, yet(More)
BACKGROUND Diabetes mellitus (DM) and aortic stenosis (AS) are frequent findings in the elderly population. Data regarding the influence of DM on the outcomes of patients undergoing transcatheter aortic valve replacement (TAVR) due to AS are limited. The aim of this study was to examine the impact of DM on TAVR outcomes. METHODS We investigated 443(More)
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