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In this paper, we present a method for incremental on-line adaptation based on feature space Maximum Likelihood Linear Regression (FMLLR) for telephony speech recognition applications. We explain how to incorporate a feature space MLLR transform into a stack decoder and perform on-line adaptation. The issues discussed are as follows: collecting adaptation(More)
Linear Discriminant Analysis (LDA) aims to transform an original feature space to a lower dimensional space with as little loss in discrimination as possible. We introduce a novel LDA matrix computation that incorporates confusability information between classes into the transform. Our goal is to improve discrimination in LDA. In conventional LDA, a between(More)
In [14], a new local minimax method that characterizes a saddle point as a solution to a local minimax problem is established. Based on the local characterization, a numerical minimax algorithm is designed for finding multiple saddle points. Numerical computations of many examples in semilinear elliptic PDE have been successfully carried out to solve for(More)
Most minimax theorems in critical point theory require to solve a two-level global optimization problem and therefore are not for algorithm implementation. The objective of this research is to develop numerical algorithms and corresponding mathematical theory for finding multiple saddle points in a stable way. In this paper, inspired by the numerical works(More)
Human neuroimaging studies and animal models have suggested that white matter damage from ischemic stroke leads to the functional and structural reorganization of perilesional and remote brain regions. However, the quantitative relationship between the transcallosal tract integrity and clinical motor performance score after stroke remains unexplored. The(More)
Four novel amicoumacins, namely lipoamicoumacins A-D (1-4), and one new bacilosarcin analog (5) were isolated from culture broth of a marine-derived bacterium Bacillus subtilis, together with six known amicoumacins. Their structures were elucidated on the basis of extensive spectroscopic (2D NNR, IR, CD and MS) analysis and in comparison with data in(More)
Two new antimycin A analogues, antimycin B1 and B2 (1-2), were isolated from a spent broth of a marine-derived bacterium, Streptomyces lusitanus. The structures of 1 and 2 were established on the basis of spectroscopic analyses and chemical methods. The isolated compounds were tested for their anti-bacterial potency. Compound 1 was found to be inactive(More)
Most minimax theorems in critical point theory require one to solve a two-level global optimization problem and therefore are not for algorithm implementation. The objective of this research is to develop numerical algorithms and corresponding mathematical theory for nding multiple saddle points in a stable way. In this paper, inspired by the numerical(More)
Chemical examination of the stems and twigs of the mangrove plant Excoecaria agallocha L. resulted in the isolation of six ent-kaurane diterpenoids named agallochaols K-P (1-6), an atisane-type diterpenoid agallochaol Q (7), along with eight known diterpenoids (8-15). Their structures were elucidated on the basis of extensive spectroscopic analysis and by(More)
The muscarinic potassium current Ik(ACh) of atrial myocytes can be evoked in the absence of agonists by intracellular application of stable GTP analogs (GXP). This receptor-independent opening of KACh channels is a consequence of the direct activation of the guanyl nucleotide binding protein Gk that couples muscarinic receptors to KACh channels, and was(More)