Yongwei Yang

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LASP1 is an actin-binding protein associated with actin assembly dynamics in cancer cells. Here, we report that LASP1 is overexpressed in pancreatic ductal adenocarcinoma (PDAC) where it promotes invasion and metastasis. We found that LASP1 overexpression in PDAC cells was mediated by HIF1α through direct binding to a hypoxia response element in the LASP1(More)
Polysaccharides, such as alginates, are already being used as carriers for drug delivery. The physicochemical and biological properties of alginates may be affected via irradiation and thermal treatments. To explore and compare effects of two kinds of sterilization methods, gamma irradiation and moist heat, on sodium alginate (SA), physicochemical and(More)
Using uniform random design optimization and the mathematical model equation we optimized the regeneration tissue culture system of the chilli pepper. An efficient and detailed plant reproducible protocol in vitro has been established using different explants and induction media for three chilli pepper cultivars. The result displayed that the seedlings at(More)
Late embryogenesis abundant (LEA) proteins in organisms are closely associated with resistance to abiotic stresses. Here we characterized a rice LEA protein, OsLEA3-1, by bioinformatics analysis and heterologous expression in Escherichia coli. Bioinformatics analysis showed that OsLEA3-1 contains a 603-bp open reading frame encoding a putative polypeptide(More)
Coronatine insensitive 1 (COI1) is a key regulator in the jasmonate signaling pathway, which plays a central role in jasmonate signaling by forming SCF complexes in the ubiquitination pathway. In this study, the full-length cDNA of CaCOI1 was isolated from chili pepper by reverse transcription PCR. CaCOI1 contains a 1,812-bp open reading frame encoding 603(More)
LASP1 is an actin-binding protein associated with actin assembly dynamics in cancer cells.Here,we report that LASP1 isoverexpressed in pancreatic ductal adenocarcinoma (PDAC) where it promotes invasion and metastasis. We found that LASP1 overexpression in PDAC cells was mediated by HIF1a through direct binding to a hypoxia response element in the LASP1(More)
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