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PI3-kinase inhibition synergistically promoted the anti-tumor effect of lupeol in hepatocellular carcinoma
BackgroundLup-20(29)-en-3H-ol (Lupeol), a dietary triterpene, has been shown to possess multiple pharmacological activities including anti-tumor effectsMethodsIn the current study, we noted that lowExpand
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The derivatives of Pulsatilla saponin A, a bioactive compound from Pulsatilla chinensis: Their synthesis, cytotoxicity, haemolytic toxicity and mechanism of action.
The strong haemolytic toxicity of Pulsatilla saponin A (PSA) has hampered its clinical development as an injectable anticancer agent. To circumvent this challenge, twenty PSA derivatives with C ringExpand
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Challenges and Research in Managing Blood Supply in China☆
Abstract Although considerable progress has been made in improving the blood service system in China over the last 2 decades, many challenges remain. A number of issues have received publicExpand
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Synthesis, cytotoxicity and haemolytic activity of Pulsatilla saponin A, D derivatives.
The strong haemolytic activity of Pulsatilla saponin A (PSA), D (PSD) hampered their clinical development of antitumor agents. In order to solve this problem, C-28 position modification derivativesExpand
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Effect of pre-thermal treatment on the lithium storage performance of LiNi0.8Co0.15Al0.05O2
Layered LiNi0.8Co0.15Al0.05O2 cathode materials have been synthesized by co-precipitation methods. The effect of pre-thermal treatment was investigated by thermogravimetric differential thermalExpand
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Research status in preparation of FePO4: a review
The cathode is the most important component of a lithium-ion battery. The olivine structure lithium iron phosphate (LiFePO4) with its numerous appealing features, such as high theoretical capacity,Expand
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Photochemically Inactivated Hepatitis B Virus Promotes Upregulation of Th1‐Type Cytokines
Photochemical virus inactivation technology is widely used to improve the safety of blood products. However, the process by which this inactivation occurs and the resulting immunogenicity of treatedExpand
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Efficient Therapeutic Function and Mechanisms of Human Polyclonal CD8+CD103+Foxp3+ Regulatory T Cells on Collagen-Induced Arthritis in Mice
  • J. Sun, Y. Yang, +9 authors J. Yang
  • Chemistry, Medicine
  • Journal of immunology research
  • 19 February 2019
Objective To investigate the potential therapeutic effect in a rheumatoid arthritis model of stable human CD8+ regulatory T cells (hCD8+Tregs) induced by TGF-β1 and rapamycin (RAPA) in vitro. MethodsExpand
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