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Anti-platelet activity of panaxatriol saponins is mediated by suppression of intracellular calcium mobilization and ERK2/p38 activation
BackgroundIncreased platelet aggregation is implicated in the pathogenesis of ischemic stroke and anti-platelet strategy may contribute to its therapy. Panaxatriol saponin (PTS), the main componentsExpand
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Panaxatriol Saponins Attenuated Oxygen-Glucose Deprivation Injury in PC12 Cells via Activation of PI3K/Akt and Nrf2 Signaling Pathway
Panaxatriol saponins (PTS), the main components extracted from Panax notoginseng, have been shown to be efficacious in the prevention and treatment of cerebrovascular diseases in China. NF-E2-relatedExpand
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Traditional uses, botany, phytochemistry, pharmacology, separation and analysis technologies of Euonymus alatus (Thunb.) Siebold: A comprehensive review.
ETHNOPHARMACOLOGICAL RELEVANCE Euonymus alatus (Thunb.) Siebold (E. alatus), a well-known medicinal plant, has been widely used thousands of years in China for the treatment of various diseases suchExpand
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Ginsenosides for the treatment of metabolic syndrome and cardiovascular diseases: Pharmacology and mechanisms.
Epidemiological studies showed that the metabolic syndromes (MetS) and cardiovascular diseases (CVDs) are responsible for a serious threat to human health worldwide. MetS is a syndromes characterizedExpand
HIF-1α is a Potential Molecular Target for Herbal Medicine to Treat Diseases
Abstract HIF-1α is an important factor regulating oxygen balance in mammals, and its expression is closely related to various physiological and pathological conditions of the body. Because HIF-1αExpand
The mechanisms of colorectal cancer cell mesenchymal–epithelial transition induced by hepatocyte exosome-derived miR-203a-3p
Abstract Phosphatase of regenerating liver 3 (PRL3) promotes colorectal cancer (CRC) metastasis by inducing epithelial-to-mesenchymal transition. Mesenchymal-to-epithelial transition (MET), theExpand
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MicroRNA-137 exerts protective effects on hypoxia-induced cell injury by inhibiting autophagy/mitophagy and maintaining mitochondrial function in breast cancer stem-like cells
Breast cancer stem-like cells (BCSCs) have been identified and proven to play critical roles in tumorigenesis and progression. Hypoxia is a common pathologic feature of breast cancer and potentially,Expand
Identification of different species of Zanthoxyli Pericarpium based on convolution neural network
Zanthoxyli Pericarpium (ZP) are the dried ripe peel of Zanthoxylum schinifolium Sieb. Expand