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BACKGROUND The induction of specific immune tolerance for alloantigen is the best method for solving transplant rejection. We have previously reported T-cell tolerance induced by RNA interference (RNAi) RelB dendritic cells (DCs), supporting the possibility of immunologic tolerance in liver transplantation. METHODS A stable model of acute rejection was(More)
We introduce a master constraint operator M̂ densely defined in the diffeomorphism invariant Hilbert space in loop quantum gravity, which corresponds classically to the master constraint in the programme. It is shown that M̂ is positive and symmetric, and hence has its Friedrichs self-adjoint extension. The same conclusion is tenable for an alternative(More)
The four-dimensional metric f(R) theories of gravity are cast into connection-dynamical formalism with real su(2) connections as configuration variables. Through this formalism, the classical metric f(R) theories are quantized by extending the loop quantization scheme of general relativity. Our results imply that the nonperturbative quantization procedure(More)
We introduce a Master Constraint Operator M̂ densely defined in the diffeomorphism invariant Hilbert space in loop quantum gravity. The corresponding quadratic form coincides with the one proposed by Thiemann in the master constraint programme. It is shown that M̂ is positive and symmetric, and hence has its Friedrichs self-adjoint extension. So the master(More)
Semiclassical states in isotropic loop quantum cosmology are employed to show that the improved dynamics has the correct classical limit. The effective Hamiltonian for the quantum cosmological model with a massless scalar field is thus obtained, which incorporates also the next to leading order quantum corrections. The possibility that the higher order(More)
In recent twenty years, loop quantum gravity, a background independent approach to unify general relativity and quantum mechanics, has been widely investigated. We consider the quantum dynamics of a real massless scalar field coupled to gravity in this framework. A Hamiltonian operator for the scalar field can be well defined in the coupled diffeomorphism(More)
Next-generation sequencing (NGS) greatly promotes the research and development of whole-genome sequencing technology. Genomic sequence assemblers and algorithms dealing with high-throughput short-read data have been the cutting-edge issues in the field. This paper discusses several latest sequence assemblers and their algorithms, and conducts a comparative(More)
A 4-dimensional Lorentzian static space-time is equivalent to 3-dimensional Euclidean gravity coupled to a massless Klein-Gordon field. By quantizing canonically the coupling model in the framework of loop quantum gravity, we obtain a quantum theory which actually describes quantized static space-times. The Kinematical Hilbert space is the product of the(More)