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Mouse mammary tumor virus-like virus infection and the risk of human breast cancer: a meta-analysis.
- Faliang Wang, Jinchao Hou, +4 authors Hongchuan Jin
- American journal of translational research
- 15 May 2014
A systematic search of multiple bibliographic databases and meta-analysis of published studies revealed a significantly increased risk for breast cancer development after MMTV-LV infection, which is much higher in breast cancer patients from Western countries than Asian patients. Expand
YY1-MIR372-SQSTM1 regulatory axis in autophagy
An epigenetic regulation of autophagy in human cancer cells is reported and YY1-promoted SQSTM1 upregulation might be a useful histological marker for cancer detection and a potential target for drug development. Expand
Function and clinical potential of microRNAs in hepatocellular carcinoma.
The aim of the present review was to summarize the most recent findings on the functions of miRNAs in the liver and discuss their potential roles in the diagnosis, prognosis and treatment of HCC. Expand
Downregulation of histone deacetylase 1 by microRNA‐520h contributes to the chemotherapeutic effect of doxorubicin
The upregulation of HDAC1 protein may contribute to drug resistance of human cancer cells and targetingHDAC1 is a promising strategy to increase the clinical efficacy of DNA damage‐inducing chemotherapeutic drugs. Expand
Histone deacetylase 3 inhibits new tumor suppressor gene DTWD1 in gastric cancer.
- Yanning Ma, Yongfang Yue, +10 authors Hongchuan Jin
- Biology, Medicine
- American journal of cancer research
- 15 January 2015
DTWD1 was downregulated in gastric cancer by HDAC3 and acted as a novel tumor suppressor gene, as the new p53 target gene, in this study. Expand
CNN3 acts as a potential oncogene in cervical cancer by affecting RPLP1 mRNA expression
It is verified that CNN3 acts as an oncogene to promote the viability and motility of cervical cancer cells in vitro and accelerate the growth and metastasis of xenografted tumours in vivo, by affecting RPLP1 expression. Expand
Interleukin-37: A crucial cytokine with multiple roles in disease and potentially clinical therapy.
The aim of this review is to outline the current knowledge of IL-37, including the location, structure, expression, regulation and function, as well as the potential clinical applications of this cytokine. Expand
Inhibitory effect of β-elemene on human breast cancer cells.
- Chaying Guan, Weiguo Liu, Yongfang Yue, Hongchuan Jin, Xian Wang, Xiaojia Wang
- Biology, Medicine
- International journal of clinical and…
- 15 June 2014
It is found that β-elemene significantly inhibited the in vitro growth of human breast cancer cells by inducing apoptosis and combination of β- elemene with autophagy inhibitors could be a promising strategy for the treatment of breast cancer. Expand
Increased Circulating MicroRNA-155 as a Potential Biomarker for Breast Cancer Screening: A Meta-Analysis
The current evidence suggests that circulating microRNA-155 has the potential diagnostic value with a high sensitivity and specificity for BC and more prospective studies on the diagnostic value of circulating miR-155 for BC are needed in the future. Expand
STON2 negatively modulates stem-like properties in ovarian cancer cells via DNMT1/MUC1 pathway
- Shanshan Xu, Yongfang Yue, +5 authors W. Lu
- Chemistry, Medicine
- Journal of experimental & clinical cancer…
- 5 December 2018
It is shown that STON2 negatively modulates the stem-like properties of ovarian cancer cells, which are characterized by sphere formation, a CD44+CD24− ratio, and by CSC- and epithelial mesenchymal transition (EMT)-related markers. Expand