Alpha-Ketoglutarate: Physiological Functions and Applications
- N. Wu, Mingyao Yang, U. Gaur, Huailiang Xu, Yongfang Yao, Diyan Li
- BiologyBiomolecules & Therapeutics
- 1 January 2016
Alpha-ketoglutarate not only extends lifespan, but also delays age-related disease and can be used in clinical applications.
Genome-Wide Survey of Pseudogenes in 80 Fully Re-sequenced Arabidopsis thaliana Accessions
- Long Wang, Weina Si, Yongfang Yao, Dacheng Tian, H. Araki, Sihai Yang
- BiologyPLoS ONE
- 13 December 2012
A significant functional bias against the null hypothesis was detected in the Ψs mainly involved in responses to environmental stimuli and biotic stress, suggesting that they are likely important for adaptive evolution to rapidly changing environments by pseudogenization to accumulate successive mutations.
Characterisation of the gut microbial community of rhesus macaques in high-altitude environments
- Yuhan Wu, Yongfang Yao, Huailiang Xu
- Biology, Environmental ScienceBMC Microbiology
- 28 January 2020
The gut microbial community of high-altitude rhesus macaques was significantly distinct from that of low-altitudes populations in terms of diversity, composition and function, and may play a critical role in the adaptive evolution of rhesu macaques to high-ALTitude environments.
The musk chemical composition and microbiota of Chinese forest musk deer males
- Diyan Li, Binlong Chen, J. Satkoski Trask
- BiologyScientific Reports
- 8 January 2016
Analysis of the chemical composition of the musk showed that unmated males have more muscone and cholesterol, and metabolic pathways such as aldosterone-regulated sodium reabsorption, metabolism of terpenoids and polyketides, flavone and flavonol biosynthesis and isoflavonoid biosynthesis were enriched in themusk of unmated Chinese forest musk deer males.
Genetic diversity and differentiation of the rhesus macaque (Macaca mulatta) population in western Sichuan, China, based on the second exon of the major histocompatibility complex class II DQB…
- Yongfang Yao, Q. Dai, Jing Li, Q. Ni, Mingwang Zhang, Huailiang Xu
- BiologyBMC Evolutionary Biology
- 14 June 2014
Phylogenetic analyses confirm the apparent trans-species model of evolution of the Mhc-DQB1 genes in these macaques, and levels of MHC variation within rhesus macaque populations are concordant with microsatellite variation.
Evolutionary conservation of the circadian gene timeout in Metazoa
- Diyan Li, Yuan Su, Mingyao Yang
The phylogeny of timeless / timeout showed an evolutionary conservation of the circadian clock gene timeout in Metazoa, in line with its multifunctionality, being essential for embryonic development and maintenance of chromosome integrity, among others.
Characterization of the Gut Microbiota in Six Geographical Populations of Chinese Rhesus Macaques (Macaca mulatta), Implying an Adaptation to High-Altitude Environment
- Junsong Zhao, Yongfang Yao, Huailiang Xu
- Biology, GeographyMicrobial Ecology
- 25 January 2018
The results suggested that in the adaptation process of rhesus macaques to different geographical environments, the abundance of the core common flora of the intestinal microbes had undergone varying degree of change and produced new and unique flora, both of which helped to reshape the gut microbiota of rhesis macaques.
Identification of Caspase-6 as a New Regulator of Alternatively Activated Macrophages*
- Yongfang Yao, Q. Shi, Pingping Shen
- Biology, ChemistryJournal of Biological Chemistry
- 20 June 2016
Alternatively activated macrophages (AAMs) play essential roles in the promotion of tissue remodeling, vasculogenesis, and tumor progression; however, the detailed mechanisms underlying the…
Characterizing the microbiota in gastrointestinal tract segments of Rhabdophis subminiatus: Dynamic changes and functional predictions
- Wenjiao Tang, Guangxiang Zhu, Diyan Li
- 7 March 2019
This is the first study to investigate the distribution of the gut microbiota and to predict the microbial function in R. subminiatus, and these findings provide vital evidence for the diagnosis and treatment of gut diseases in snakes and offer a direction for a model of energy budget research.
Evidence of adaptive evolution of alpine pheasants to high-altitude environment from mitogenomic perspective
- Peng Gu, Wei Liu, Huailiang Xu
- BiologyMitochondrial DNA. Part A, DNA mapping…
- 2 January 2016
The findings suggested that adaptive evolution may occur in alpine pheasants, which are an important complement to the knowledge of genetic mechanisms against the high-altitude environment in non-mammal animals.