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Identification of dysregulated lncRNAs profiling and metastasis‐associated lncRNAs in colorectal cancer by genome‐wide analysis
Aberrantly expressed lncRNAs may play critical roles in the development and liver metastasis of CRC, and their findings may provide useful resource for identification of novel biomarkers of CRC.
circRNAs and Exosomes: A Mysterious Frontier for Human Cancer
Over-expression of oncigenic pesudogene DUXAP10 promotes cell proliferation and invasion by regulating LATS1 and β-catenin in gastric cancer
- Yongcan Xu, Xiang Yu, Chen-chen Wei, Feng-qi Nie, Ming-de Huang, Ming Sun
- Biology, MedicineJournal of experimental & clinical cancer…
- 27 January 2018
Findings illuminate how increased DUXAP10 confers an oncogenic function in GC development and progression that may serve as a candidate prognostic biomarker and target for clinical management of GC.
DCN deficiency promotes renal cell carcinoma growth and metastasis through downregulation of P21 and E-cadherin
Examining the expression patterns of DCN messenger RNA in RCCs through the Oncomine database and DCN protein in 94 RCC specimens by immunohistochemistry revealed that DCN expression was decreased in cancerous tissues compared to adjacent noncancerous tissues and was highly correlated to tumor size.
Identification of differential expressed lncRNAs in human thyroid cancer by a genome‐wide analyses
The findings reveal that lots of lncRNAs are dysregulated and may play critical roles in thyroid cancer, and this study could provide useful resource for identification and investigation of novel lncRNA candidates for thyroid cancer.
Up-regulated long non-coding RNA DUXAP8 promotes cell growth through repressing Krüppel-like factor 2 expression in human hepatocellular carcinoma
It is revealed that down-regulation of lncRNA DUXAP8 inhibited HCC cells proliferation and colony formation ability and can provide a valuable resource of HCC-associated lncRNAs and new insights into the biological functions of l NCRNAs in HCC development.
A genome-wide comprehensively analyses of long noncoding RNA profiling and metastasis associated lncRNAs in renal cell carcinoma
A lot of lncRNAs are aberrantly expressed in RCC that may offer useful resource for identification novel prognostic markers in this disease, and some novel metastasis associated lnc RNAs in R CC are identified.
The emerging regulatory roles of long non-coding RNAs implicated in cancer metabolism.
TMED6-COG8 is a novel molecular marker of TFE3 translocation renal cell carcinoma.
- Yongcan Xu, Q. Rao, Xiao-jun Zhou
- Biology, MedicineInternational journal of clinical and…
- 1 March 2015
Owing to recent advances in microarray and RNA-Seq, Pflueger et al. have discovered that TMED6-COG8 is dramatically increased in TFE3 translocation RCCs, compared with clear cell R CCs and papillary RCCS, implying that TMed6- COG8 might be a new molecular tumor marker of TFE 3 translocationRCCs.
Long noncoding RNA GAS5 inhibits proliferation and metastasis in papillary thyroid carcinoma through the IFN/STAT1 signaling pathway.