Yong-cheng Sun

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LL-37 displays potent broad-spectrum activity against a number of pathogenic bacteria and is the only cathelicidin thus far identified in humans. In this study, we examined the capacity of human LL-37 and the similar CAP-18-derived peptide from rabbits to exert antimicrobial activity against the causative agent of syphilis, Treponema pallidum. We found that(More)
Yaws, caused by Treponema pallidum ssp. pertenue, is a neglected tropical disease closely related to venereal syphilis and is targeted for eradication by 2020. Latent yaws represents a diagnostic challenge, and current tools cannot adequately distinguish between individuals with true latent infection and individuals who are serofast following successful(More)
Time Petri Nets (TPNs) are a popular Petri net model for specification and verification of real-time systems. A widely applied method for analyzing Petri nets is component-level reduction analysis. The existing technique for component-level reduction analysis transforms a TPN component to a constant size of simple one while maintains the net external(More)
OBJECTIVE To investigate the influence of chronic epilepsy on spatial memory retrieval in rats, and to evaluate the effects of TAK-147, an acetylcholinesterase inhibitor, and histidine, the precursor of histamine, on the amnesia induced by epilepsy. METHODS After successfully trained in the 8-arm (4-arm baited) radial maze, the rats were ip injected with(More)
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