• Publications
  • Influence
Adhesive/Dentin Interface: The Weak Link in the Composite Restoration
  • P. Spencer, Q. Ye, J. Katz
  • Medicine, Materials Science
    Annals of Biomedical Engineering
  • 27 February 2010
The article will examine the various avenues that have been pursued to address problems and it will explore how alterations in material chemistry could address the detrimental impact of physico-chemical stresses on the bond formed at the adhesive/dentin interface.
Adhesive phase separation at the dentin interface under wet bonding conditions.
The morphologic results in corroboration with the spectroscopic data suggest that as a result of adhesive phase separation the hybrid layer is not an impervious 3-dimensional collagen/polymer network but a porous web characterized by hydrophobic BisGMA-rich particles distributed in a hydrophilic HEMA-rich matrix.
Chemical profile of adhesive/caries-affected dentin interfaces using Raman microspectroscopy.
The results indicated that the differences in the Raman spectra between noncarious and caries-affected dentin could not be accounted for by simple decreased mineralization and led to greater variability and a more highly irregular composition along the length and breadth of the interface.
BisGMA/TEGDMA dental composite containing high aspect-ratio hydroxyapatite nanofibers.
Relationship of solvent to the photopolymerization process, properties, and structure in model dentin adhesives.
The purpose of this investigation was to study the relationship of photopolymerization processes, bulk properties, and structure using model dentin adhesives cured in the presence of different ethanol content as an example.
Cross-linked demineralized dentin maintains its mechanical stability when challenged by bacterial collagenase.
  • Changqi Xu, Yong Wang
  • Materials Science
    Journal of biomedical materials research. Part B…
  • 1 February 2011
It is suggested that improving the degree of crosslinking in dentin collagen could be one method to inhibit its biodegradation and further to increase the durability of dental restorations.
Confocal Laser Raman Microspectroscopy of Biomineralization Foci in UMR 106 Osteoblastic Cultures Reveals Temporally Synchronized Protein Changes Preceding and Accompanying Mineral Crystal Deposition*
Raman spectral data demonstrate for the first time that formation of hydroxyapatite crystals within individual BMF is a multistep process and changes in protein-derived signals at 1004 and 1660 cm-1 reflect events within BMFs that precede or accompany mineral crystal production because they are blocked by mineralization inhibitor 4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride.
Histomorphologic characterization of noncarious and caries-affected dentin/adhesive interfaces.
The morphologic characteristics of the caries-affected dentin/interface suggest an increase in the exposed collagen zone and a decrease in the quality of the adhesive infiltration when compared with noncarious dentin.
Collagen cross linking increases its biodegradation resistance in wet dentin bonding.
  • Changqi Xu, Yong Wang
  • Materials Science, Chemistry
    The journal of adhesive dentistry
  • 1 February 2012
The results corroborate the previous findings that by using the current adhesive system and wet bonding, the collagen fibrils in the a/d interface are largely unprotected and easily undergo biodegradation.