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- Publications
- Influence
Inhibitory cross‐talk between the AMPK and ERK pathways mediates endoplasmic reticulum stress‐induced insulin resistance in skeletal muscle
- Seung-Lark Hwang, Yong-Tae Jeong, +5 authors H. Chang
- Biology, Medicine
- British journal of pharmacology
- 1 May 2013
Endoplasmic reticulum (ER) stress has been implicated in the pathogeneses of insulin resistance and type 2 diabetes, and extracellular signal‐regulated kinase (ERK) antagonist is an insulin… Expand
Antitumor and immunomodulating activities of endo-biopolymers obtained from a submerged culture of Pleurotus eryngii
- Yong-Tae Jeong, Sang-Chul Jeong, Young-Ah Gu, R. Islam, Chi-Hyun Song
- Chemistry
- 30 April 2010
Antitumor effect of endo-biopolymer (EBP) obtained from submerged mycelial culture of Pleurotus eryngii was investigated by using Sarcoma-180 bearing mice. The administration of EBP,… Expand
Emodin Isolated from Polygoni cuspidati Radix Inhibits TNF-α and IL-6 Release by Blockading NF-κB and MAP Kinase Pathways in Mast Cells Stimulated with PMA Plus A23187
- Y. Lu, Yong-Tae Jeong, +5 authors H. Chang
- Medicine
- Biomolecules & therapeutics
- 1 November 2013
Emodin, a naturally occurring anthraquinone derivative isolated from Polygoni cuspidati radix, has several beneficial pharmacologic effects, which include anti-cancer, anti-diabetic, and… Expand
Low Molecular Weight Fucoidan Improves Endoplasmic Reticulum Stress-Reduced Insulin Sensitivity through AMP-Activated Protein Kinase Activation in L6 Myotubes and Restores Lipid Homeostasis in a…
- Yong-Tae Jeong, Y. Kim, +12 authors H. Chang
- Chemistry, Medicine
- Molecular Pharmacology
- 8 May 2013
Low molecular weight fucoidan (LMWF) is widely used to treat metabolic disorders, but its physiologic effects have not been well determined. In the present study, we investigated the metabolic… Expand
AMP-activated protein kinase negatively regulates FcεRI-mediated mast cell signaling and anaphylaxis in mice.
- Seung-Lark Hwang, X. Li, +9 authors H. Chang
- Chemistry, Medicine
- The Journal of allergy and clinical immunology
- 1 September 2013
BACKGROUND
Aggregation of FcεRI activates a cascade of signaling events leading to mast cell activation, followed by inhibitory signals that turn off the activating signals. However, the overall view… Expand
Ganoderma applanatum: a promising mushroom for antitumor and immunomodulating activity
- Yong-Tae Jeong, B. Yang, Sang-Chul Jeong, Sang-min Kim, Chi-Hyun Song
- Biology, Medicine
- Phytotherapy research : PTR
- 1 May 2008
The antitumor effect of exo‐biopolymer (EXP) produced by Ganoderma applanatum was investigated using sarcoma‐180 bearing mice. EXP, when administered (10–80 mg/kg body weight: BW) intraperitoneally,… Expand
Glyceollin improves endoplasmic reticulum stress-induced insulin resistance through CaMKK-AMPK pathway in L6 myotubes.
- Eun-Kyung Yoon, Yong-Tae Jeong, +7 authors Seung-Lark Hwang
- Biology, Medicine
- The Journal of nutritional biochemistry
- 1 June 2013
Glyceollin has been shown to have antidiabetic properties, although its molecular mechanism is not known. Here, we have investigated the metabolic effects of glyceollin in animal models of insulin… Expand
Hypolipidemic Effects of Biopolymers Extracted from Culture Broth, Mycelia, and Fruiting Bodies of Auricularia auricula-judae in Dietary-induced Hyperlipidemic Rats
- H. Jeong, B. Yang, +5 authors Chi-Hyun Song
- Biology, Medicine
- Mycobiology
- 1 March 2007
Hypolipidemic effect of biopolymers extracted from culture broth (CP), mycelia (MP), and fruiting bodies (FP) of Auricularia auricula-judae was investigated in dietary-induced hyperlipidemic rats.… Expand
Optimal Culture Conditions for Mycelial Growth and Exo-polymer Production of Ganoderma applanatum
- Yong-Tae Jeong, Sang-Chul Jeong, B. Yang, R. Islam, Chi-Hyun Song
- Biology, Medicine
- Mycobiology
- 1 June 2009
The effect of fermentation parameters and medium composition on the simultaneous mycelial growth and exo-polymer production from submerged cultures of Ganoderma applanatum was investigated in… Expand
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