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- Publications
- Influence
Acute and subacute toxicity profiles of thymoquinone-loaded nanostructured lipid carrier in BALB/c mice
- Yong Sze Ong, Latifah Saiful Yazan, +4 authors Y. S. Tor
- Chemistry, Medicine
- International journal of nanomedicine
- 9 November 2016
Background Thymoquinone (TQ), the predominant active lipophilic component in Nigella sativa seed oil, has a variety of pharmacological properties such as anticancer activities. However, translation… Expand
Chemopreventive Properties and Toxicity of Kelulut Honey in Sprague Dawley Rats Induced with Azoxymethane
- Latifah Saiful Yazan, Muhamad Firdaus Shyfiq Muhamad Zali, +8 authors Sharifah Sakinah Syed Alwi
- Chemistry, Medicine
- BioMed research international
- 25 July 2016
Ethnopharmacological Relevance. Colon cancer has been a major problem worldwide. Kelulut honey (KH) is produced by the stingless bees from Trigona species and has strong antioxidant activities that… Expand
Thymoquinone loaded in nanostructured lipid carrier showed enhanced anticancer activity in 4T1 tumor-bearing mice.
- Yong Sze Ong, Latifah Saiful Yazan, +8 authors Fatin Hannani Zakarial Ansar
- Chemistry, Medicine
- Nanomedicine
- 1 July 2018
AIM
To investigate the enhancement of anticancer activity of thymoquinone (TQ) by the use of nanostructured lipid carrier (NLC) in 4T1 tumor-bearing female BALB/c mice.
MATERIAL & METHODS
TQ was… Expand
Induction of apoptosis and G2/M arrest by ampelopsin E from Dryobalanops towards triple negative breast cancer cells, MDA-MB-231
- Napsiah Abd Rahman, L. S. Yazan, +7 authors S. Fakurazi
- Medicine
- BMC Complementary and Alternative Medicine
- 8 September 2016
BackgroundSeveral compounds isolated from Dryobalanops have been reported to exhibit cytotoxic effects to several cancer cell lines. This study investigated the cytotoxic effects, cell cycle arrest… Expand
Cytotoxic Effect of Thymoquinone-Loaded Nanostructured Lipid Carrier (TQ-NLC) on Liver Cancer Cell Integrated with Hepatitis B Genome, Hep3B
- Aminah Suhaila Haron, Sharifah Sakinah Syed Alwi, +4 authors Henna Roshini Alexander
- Chemistry, Medicine
- Evidence-based complementary and alternative…
- 16 August 2018
Thymoquinone (TQ), a bioactive compound found in Nigella sativa, cannot be orally consumed due to its lipophilicity. In order to overcome this low bioavailability, TQ is loaded into a colloidal drug… Expand
Anti-breast cancer properties and toxicity of Dillenia suffruticosa root aqueous extract in BALB/c mice
- L. S. Yazan, Yong Sze Ong, Nur Elena Zaaba, R. M. Ali, J. B. Foo, Y. S. Tor
- Medicine
- 1 December 2015
Abstract Objective To determine the anti-breast cancer activities and the safety oral consumption of Dillenia suffruticosa root aqueous extract (DRAE) in BALB/c mice. Methods In the anti-breast… Expand
Migration and Proliferation Effects of Thymoquinone-Loaded Nanostructured Lipid Carrier (TQ-NLC) and Thymoquinone (TQ) on In Vitro Wound Healing Models
- Henna Roshini Alexander, Sharifah Sakinah Syed Alwi, L. S. Yazan, Fatin Hannani Zakarial Ansar, Yong Sze Ong
- Chemistry, Medicine
- Evidence-based complementary and alternative…
- 29 November 2019
Wound healing is a regulated biological event that involves several processes including infiltrating leukocyte subtypes and resident cells. Impaired wound healing is one of the major problems in… Expand
An Optimized Anti-adherence and Anti-biofilm Assay: Case Study of Zinc Oxide Nanoparticles versus MRSA Biofilm
- Hefa Mangzira Kemung, Loh Teng-Hern Tan, +5 authors B. Goh
- Chemistry
- 12 June 2020
Biofilms form protective layers over bacteria that are associated with a majority of the hospital infections contributing to antibiotic resistance development in susceptible strains. Nowadays, there… Expand
Antiulcer properties of Kelulut honey against ethanol-induced gastric ulcer
- L. S. Yazan, Nurul Amira Zainal, +11 authors S. N. S. Alwi
- Medicine
- 2018
Ulcers in the gastrointestinal tract refer to any appreciable depth of break in the mucosa lining that may involve submucosa. Common types of ulcer include peptic, gastric and duodenal ulcer, which… Expand
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Cancer, Natural Products and Nanodrug Delivery Systems
- Yong Sze Ong, Loh Teng-Hern Tan
- Medicine
- 5 June 2020
As an offshoot of nanotechnology, nanomedicine has made great impact in the field of pharmaceutical and biomedical sciences by achieving breakthroughs in therapeutics and diagnostics of diseases in… Expand