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Induction of apoptosis and G2/M arrest by ampelopsin E from Dryobalanops towards triple negative breast cancer cells, MDA-MB-231

• Napsiah Abd Rahman, Latifah Saiful Yazan, +7 authors Sharida Fakurazi
• BMC Complementary and Alternative Medicine
• 2016

BackgroundSeveral compounds isolated from Dryobalanops have been reported to exhibit cytotoxic effects to several cancer cell lines. This study investigated the cytotoxic effects, cell cycle arrest… (More)

Chemopreventive Properties and Toxicity of Kelulut Honey in Sprague Dawley Rats Induced with Azoxymethane

• Latifah Saiful Yazan, Muhamad Firdaus Shyfiq Muhamad Zali, +8 authors Sharifah Sakinah Syed Alwi
• BioMed research international
• 2016

Ethnopharmacological Relevance. Colon cancer has been a major problem worldwide. Kelulut honey (KH) is produced by the stingless bees from Trigona species and has strong antioxidant activities that… (More)

Acute and subacute toxicity profiles of thymoquinone-loaded nanostructured lipid carrier in BALB/c mice

• Yong Sze Ong, Latifah Saiful Yazan, +4 authors Yin Sim Tor
• International journal of nanomedicine
• 2016

BACKGROUND Thymoquinone (TQ), the predominant active lipophilic component in Nigella sativa seed oil, has a variety of pharmacological properties such as anticancer activities. However, translation… (More)

Anti-breast cancer properties and toxicity of Dillenia suffruticosa root aqueous extract in BALB/c mice

• Latifah Saiful Yazan, Yong Sze Ong, Nur Elena Zaaba, Razana Mohd Ali, J. B. Foo, Yin Sim Tor
• 2015

Abstract Objective To determine the anti-breast cancer activities and the safety oral consumption of Dillenia suffruticosa root aqueous extract (DRAE) in BALB/c mice. Methods In the anti-breast… (More)

Antiulcer properties of Kelulut honey against ethanol-induced gastric ulcer

• Latifah Saiful Yazan, Nurul Amira Zainal, +11 authors Sharifah S. Syed Alwi
• 2018

Ulcers in the gastrointestinal tract refer to any appreciable depth of break in the mucosa lining that may involve submucosa. Common types of ulcer include peptic, gastric and duodenal ulcer, which… (More)

Cytotoxic Effect of Thymoquinone-Loaded Nanostructured Lipid Carrier (TQ-NLC) on Liver Cancer Cell Integrated with Hepatitis B Genome, Hep3B

• Aminah Suhaila Haron, Sharifah Sakinah Syed Alwi, +4 authors Henna Roshini Alexander
• Evidence-based complementary and alternative…
• 2018

Thymoquinone (TQ), a bioactive compound found in Nigella sativa, cannot be orally consumed due to its lipophilicity. In order to overcome this low bioavailability, TQ is loaded into a colloidal drug… (More)