Yong-Qing Wang

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OBJECTIVE To evaluate the feasibility and accuracy of cervical spine pedicle screw fixation assisted by X-ray fluoroscopy and CT-based navigation system. METHODS 145 cervical pedicle screws were placed assisted by X-ray fluoroscopy and 159 cervical pedicle screws were placed assisted by CT-based navigation system. Screw positions were evaluated by(More)
INTRODUCTION H(+)/K(+)-ATPase is a P-type ATP-driven cation transporter which exchanges ions (protons, chloride ions, and potassium ions) across the cell membrane. Modulators of H(+)/K(+)-ATPase affect H(+)/K(+) exchange. AREAS COVERED This article describes various H(+)/K(+)-ATPase inhibitors of biological importance in clinical studies and drug(More)
This study aimed to investigate the therapeutic effects of epigallocatechin-3-gallate (EGCG) administered by subarachnoid injection following spinal cord injury (SCI) in rats and to explore the underlying mechanism. Sprague–Dawley rats were randomly divided into four groups of 12 as follows: a sham group (laminectomy only); a control group; a 10 mg/kg(More)
STUDY DESIGN Retrospective case series. OBJECTIVE To evaluate the accuracy of screw fixation using intraoperative three-dimensional fluoroscopy-based navigation (ITFN) and to assess the clinical outcomes of this treatment regimen. SUMMARY OF BACKGROUND DATA The surgical management of symptomatic os odontoideum poses considerable difficulties due to the(More)
BACKGROUND Proton pump inhibitors (PPIs) are a group of gastric acid suppressing drugs, they work by irreversibly blocking the H+/K+ ATPase. The structure of PPIs is similar. They all have a similar core with a sulphur atom chiral center combined with different substituent groups. In relation to the sulphur atom chiral center, the pharmacodynamics,(More)
The objective of this study was to investigate the effectiveness of additional intraoperative mechanical dilatation of the pyloric sphincter in order to prevent early postoperative gastric retention after esophagectomy using the stomach as substitute for esophageal carcinoma patients. Between October 2001 and May 2002, 32 consecutive esophageal carcinoma(More)
AIM To investigate whether bone marrow-derived denritic cells pulsed with tumor lysates induce immunity against gastric cancer ex vivo. METHODS c-kit(+) hematopoietic progenitor cells were magnetically isolated with a MiniMACS separator from BALB/c mice bone marrow cells. These cells were cultured with cytokines GM-CSF, IL-4, and TNFalpha to induce their(More)
INTRODUCTION FK506-binding protein 12 (FKBP12) is an endogenous protein with peptidyl-prolyl isomerase (PPIase) activity. Natural compounds FK506, rapamycin and ascomycin, are FKBP12 ligands used for treating organ transplant rejection and other diseases. Small ligands that also interact with FKBP12 are designed and synthetized based on the natural ligands.(More)
Well-defined Li(4)Ti(5)O(12) nanosheets terminated with rutile-TiO(2) at the edges were synthesized by a facile solution-based method and revealed directly at atomic resolution by an advanced spherical aberration imaging technique. The rutile-TiO(2) terminated Li(4)Ti(5)O(12) nanosheets show much improved rate capability and specific capacity compared with(More)
Postmediastinal schwannoma is a kind of neurogenic tumor originating from the neuron sheath in the posterior mediastinum. In the majority of cases these tumors are located in the paravertebral sulcus and the incidence is similar in both sides of the thorax as single or multiple; however, multi-schwannomas involved in the bilateral postmediastinum are rare.(More)