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Adiponectin (ADP) is an adipocyte hormone involved in glucose and lipid metabolism. We detected a rise in ADP in cerebrospinal fluid after intravenous (i.v.) injection, consistent with brain transport. In contrast to leptin, intracerebroventricular (i.c.v.) administration of ADP decreased body weight mainly by stimulating energy expenditure. Full-length(More)
Efficient aggregation of data collected by sensors is crucial for a successful application of wireless sensor networks (WSNs). Both minimizing the energy cost and reducing the time duration (or called latency) of data aggregation have been extensively studied for WSNs. Algorithms with theoretical performance guarantees are only known under the protocol(More)
Cardinality estimation and tag authentication are two major issues in large-scale Radio Frequency Identification (RFID) systems. While there exist both per-tag and probabilistic approaches for the cardinality estimation, the RFID-oriented authentication protocols are mainly per-tag based: the reader authenticates one tag at each time. For a batch of tags,(More)
Previous work has shown that the endogenous cystathionine gamma-synthase (CSE)/hydrogen sulfide (H(2)S) pathway participates in the regulation of cardiac contraction. We hypothesized that the pathway might participate in the pathophysiological regulation of ischemic heart disease. Isoproterenol injection of rat hearts induced a myocardial ischemic injury(More)
Energy efficient routing and power control techniques in wireless ad hoc networks have drawn considerable research interests recently. In this paper, we address the problem of energy efficient reliable routing for wireless ad hoc networks in the presence of unreliable communication links or devices or lossy wireless link layers by integrating the power(More)
In this paper, we address the problem of joint channel assignment, link scheduling, and routing for throughput optimization in wireless networks with multi-radios and multi-channels. We mathematically formulate this problem by taking into account the interference, the number of available radios the set of usable channels, and other resource constraints at(More)
This paper presents our joint research efforts on big data benchmarking with several industrial partners. Considering the complexity, diversity, workload churns, and rapid evolution of big data systems, we take an incremental approach in big data benchmarking. For the first step, we pay attention to search engines, which are the most important domain in(More)
Many works have been carried out to find the efficient algorithms for QoS-aware service composition in recent years. Nevertheless, on one hand, some of these works only consider the local QoS attributes in Web services composition; on the other hand, some ideas derived from QoS selection algorithms for network routing are directly applied in service(More)
BACKGROUND The epithelial-mesenchymal transition (EMT) induced by growth factors or cytokines, particularly transforming growth factor-β (TGF-β1), plays an important role in kidney tubulointerstitial injury. However, signaling pathways mediating TGF-β1-induced EMT are not precisely known. In this study, we examined the role of Akt2 on EMT. METHODS HK-2(More)
The association between obesity and diabetes supports an endocrine role for the adipocyte in maintaining glucose homeostasis. Here we report that mice lacking the adipocyte hormone resistin exhibit low blood glucose levels after fasting, due to reduced hepatic glucose production. This is partly mediated by activation of adenosine monophosphate-activated(More)