Yong-Kyu Lee

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Kami-shoyo-san (KSS), a traditional Chinese medicine, has been used to treat patients with neuropsychiatric disorders. The aim of the present paper was to investigate whether KSS has antidepressant-like effects, and to assess its mechanism of action, using male Sprague-Dawley rats given 10-fold (KSS 10X) or 20-fold (KSS 20X) the typical human daily dosage.(More)
AIMS The opioid antagonist naltrexone may reduce ethanol reward, but the underlying neurochemical mechanisms has yet to be clarified. The afferent projections to the nucleus accumbens from the ventral tegmental area (VTA) provide a potential substrate by which endogenous opioids may modulate the dopaminergic rewarding effects of ethanol. We assessed mRNA(More)
Parkinson's disease (PD) is a chronic progressive neurodegenerative disorder. Recent studies have implicated a role for peroxisome proliferator-activated receptor γ coactivator protein-1α (PGC-1α) in PD and in animal or cellular models of PD. The role of PGC-1α in the function and survival of substantia nigra pars compacta (SNpc) dopamine neurons is not(More)
BACKGROUND/AIMS Immunoglobulin A nephropathy (IgAN) is a generally progressive disease, even in patients with favorable prognostic features. In this study, we aimed to investigate the antiproteinuric effect and tolerability of low-dose valsartan (an angiotensin II receptor blocker) therapy in normotensive IgAN patients with minimal proteinuria of less than(More)
  • Anwarul Hasan, Md Nurunnabi, Alessandro Polini, Tapas Kuila, Moustafa Al Hariri, Yong-Kyu Lee +1 other
  • 2014
The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. Biosensors research is a fast growing field in which tens of thousands of papers have been published over the years, and the industry is now worth billions of dollars. The biosensor products have found their applications in numerous(More)
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