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AIMS To examine the relationship between statin use in Chinese patients with intracerebral hemorrhage (ICH) during their hospitalization and the outcomes. METHODS Data were collected from the China National Stroke Registry. Good functional outcome was defined by a modified Rankin Scale score between 0-2. Functional outcome and rate of mortality at 3(More)
BACKGROUND AND PURPOSE Little information is available on the effects of age on health care and outcomes of ischemic stroke (IS) in China. Our aim was to evaluated risk factors, health care, and outcomes among age groups including ≤ 45, 46-65, 66-79, and ≥ 80 years and to find whether the outcome was affected by age and health care. METHODS CNSR is a(More)
OBJECTIVE This study aimed to investigate the association of galanin (GAL) gene and the development of depression in the Chinese Han population. METHODS A total of 700 patients with depression who met the diagnostic criteria of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) and 673 healthy controls were used in this study.(More)
OBJECTIVE Bipolar disorder patients experiencing a depressive episode (BD-dep) without an observed history of mania are often misdiagnosed and are consequently treated as having unipolar depression (UD), leading to inadequate treatment and poor outcomes. An essential solution to this problem is to identify objective biological markers that distinguish(More)
We examined resting state brain activity in the depressive phase of bipolar disorder (BD) by measuring the amplitude of low-frequency fluctuations (ALFF) in the functional magnetic resonance imaging (fMRI) signal. Unlike functional connectivity, the ALFF approach reflects local properties in specific regions and provides direct information about impaired(More)
The different expressions of NR2 and synaptic-associated proteins have been studied by protein and mRNA level with immunoblotting, in situ hybridization, or immunogold analysis. But the relationship between NR2 subunits and PSD-95 family proteins is still controversial. In this study, we used immunofluorescent staining to assess NR2B and PSD-95 expressions(More)
AIM We sought to use a regional homogeneity (ReHo) approach as an index in resting-state functional magnetic resonance imaging (fMRI) to investigate the features of spontaneous brain activity within the default mode network (DMN) in patients suffering from bipolar depression (BD). METHODS Twenty-six patients with BD and 26 gender-, age-, and(More)
BACKGROUND The last update of the consensus statement on intravenous recombinant tissue plasminogen activator (IV rt-PA) for acute ischemic stroke (AIS) by the Chinese Stroke Therapy Expert Panel was published in 2006. Great progress has been made since then. AIM To provide another update on the new knowledge of IV rt-PA for AIS since 7 years ago. (More)