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Recent analytical approaches in quality control of traditional Chinese medicines--a review.
TLDR
The recent analytical methods in the quality control of TCMs are reviewed, including screening strategies of bioactive markers from TCMs through biochromatographic methods, the traditional chromatography methods, DNA methods, as well as the spectroscopic methods, including FT-IR, NIR and NMR. Expand
Analysis of chemical constituents in Cistanche species.
  • Yong Jiang, P. Tu
  • Chemistry, Medicine
  • Journal of chromatography. A
  • 13 March 2009
TLDR
Pharmacological studies show that PhGs are the main active components for curing kidney deficiency, antioxidation and neuroprotection; galactitol and oligosaccharides are the representatives for the treatment of senile constipation, while polysaccharide are responsible for improving body immunity. Expand
Evaluation of the anti-myocardial ischemia effect of individual and combined extracts of Panax notoginseng and Carthamus tinctorius in rats.
TLDR
The findings suggest EPN combined with ECT may be therapeutically more useful for ameliorating anti-myocardial ischemia injuries than individual herbal extract, and EPN 50mg/kg plus ECT 200mg/ kg is the appropriate combination in the present research. Expand
One single standard substance for the determination of multiple anthraquinone derivatives in rhubarb using high-performance liquid chromatography-diode array detection.
TLDR
In this study, rhubarb rhizome was selected as an example, and emodin, the easily available active component, was used as the external standard to determine directly the content of Emodin in rhubARB, and the same component as the internal standard to simultaneously determine the other six anthraquinones in Rhubarb. Expand
Sesquiterpene dimmer (DSF-27) inhibits the release of neuroinflammatory mediators from microglia by targeting spleen tyrosine kinase (Syk) and Janus kinase 2 (Jak2): Two major non-receptor tyrosine
TLDR
Findings indicate NRPTK signaling pathways including Syk/NF-κB and Jak2/Stat3 cascades are potential anti-neuroinflammatory targets in microglia, and may also set the basis for the use of sesquiterpene dimmer as a therapeutic approach for neuroinflammation via interruption of these pathways. Expand
NO inhibitory guaianolide-derived terpenoids from Artemisia argyi.
TLDR
In in vitro assay, compound 2 exhibited pronounced inhibition on the lipopolysaccharide (LPS)-induced nitric oxide (NO) production in BV-2 microglial cells with an IC50 value of 4.00μM. Expand
Nitric Oxide Inhibitory Dimeric Sesquiterpenoids from Artemisia rupestris.
TLDR
The 12 new dimeric sesquiterpenoids isolated from the dried whole plants of Artemisia rupestris exhibited moderate inhibition on NO production stimulated by lipopolysaccharide in BV-2 microglial cells, with IC50 values in the range 17.0-71.8 μM. Expand
Characterization of seventy polymethoxylated flavonoids (PMFs) in the leaves of Murraya paniculata by on-line high-performance liquid chromatography coupled to photodiode array detection and
  • Jia-yu Zhang, Ning Li, +5 authors P. Tu
  • Chemistry, Medicine
  • Journal of pharmaceutical and biomedical analysis
  • 15 December 2011
TLDR
A sensitive HPLC-DAD-ESI-MS/MS method was established to screen and identify the polymethoxylated flavonoids in the leaves of Murraya paniculata (L.) Jack and indicated that the developed analysis method could be employed as a rapid, effective technique for structural characterization of PMFs. Expand
8-C N-ethyl-2-pyrrolidinone substituted flavan-3-ols as the marker compounds of Chinese dark teas formed in the post-fermentation process provide significant antioxidative activity.
TLDR
Through single fungal fermentation, it was proved that catechins and theanine were the precursors of puerins I-VIII and could be used in the quality control and authentication of Chinese dark teas. Expand
Inhibition of Osteogenic Differentiation of Human Adipose‐Derived Stromal Cells by Retinoblastoma Binding Protein 2 Repression of RUNX2‐Activated Transcription
TLDR
This study is the first to demonstrate the functional and biological roles of H3K4 demethylase RBP2 in osteogenic differentiation of hASCs and to linkRBP2 to the transcriptional regulation of RUNX2. Expand
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