Yong-Eng Lee

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Our previous studies showed that nitric oxide (NO) could induce osteoblast apoptosis. MicroRNA-1 (miR-1), a skeletal- and cardiac muscle-specific small non-coding RNA, contributes to the regulation of multiple cell activities. In this study, we evaluated the roles of miR-1 in NO-induced insults to osteoblasts and the possible mechanisms. Exposure of mouse(More)
STUDY DESIGN Displacement-controlled finite element analysis was used to evaluate the mechanical behavior of the lumbar spine after insertion of the Dynesys dynamic stabilization system. OBJECTIVE This study aimed to investigate whether different depths of screw placement of Dynesys would affect load sharing of screw, range of motion (ROM), annulus(More)
AIM OF THIS STUDY Our previous study showed that Drynaria fortunei J. Sm. (Kunze), a traditional Chinese medical herb, can promote osteoblast differentiation and maturation. This study was further aimed to confirm the traditional effects of Kunze on the bone mass of ovariectomized rats. MATERIALS AND METHODS Female Wistar rats were given an ovariectomy(More)
Children with spina bifida (SB) can exhibit excessive arm swing, trunk sway, and pelvic tilt during walking. To understand the relationship between abnormal low back forces (LBF) and gait disorders in SB, we derived a mathematical model for evaluating LBF in this population. One unimpaired child and a child with SB were tested. A 3D motion analysis system(More)
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