Yojiro Tezuka

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We have established the nanofabrication technique for constructing nanopillars with high aspect ratio (100-500 nm diameter and 500-5000 nm tall) inside a microchannel on a quartz chip. The size of pillars and the spacing between pillars are designed as a DNA sieving matrix for optimal analysis of large DNA fragments over a few kilobase pairs (kbp). A chip(More)
We have developed nano-biodevices to accelerate genomic drug discovery and post genome sequencing researches. The nanopillar chips, which has an array of nanometer-sized pillars inside a microchannel, were successfully fabricated on quartz substrate and applied for DNA separation. The nanopillar chips showed great potential to realize fast genome analysis(More)
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