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  • Yogeshvar N Kalia, Richard H. Guy
  • Chemistry, Medicine
  • Advanced drug delivery reviews
  • 2001 (First Publication: 11 June 2001)
  • The stratum corneum forms the outermost layer of the skin and is essentially a multilamellar lipid milieu punctuated by protein-filled corneocytes that augment membrane integrity and significantlyContinue Reading
    It is, sometimes, desirable to maintain a constant plasma drug concentration within the therapeutically effective concentration range. The use of high viscosity hydromiscible vehicles such asContinue Reading
  • Yogeshwar G. Bachhav, S. Summer, A. Heinrich, Thomas Bragagna, Christof Boehler, Yogeshvar N Kalia
  • Chemistry, Medicine
  • Journal of controlled release : official journal…
  • 2010 (First Publication: 17 August 2010)
  • The objectives of this study were to investigate a novel laser microporation technology ( P.L.E.A.S.E. Painless Laser Epidermal System) and to determine the effect of pore number and depth on theContinue Reading
  • Yogeshvar N Kalia, Ingo Alberti, Nabila Sekkat, Catherine Curdy, A. Chandu Naik, Richard H. Guy
  • Medicine, Chemistry
  • Pharmaceutical Research
  • 2004 (First Publication: 1 September 2000)
  • PURPOSE : To understand and account for inter-individual variations in percutaneous drug penetration and transepidermal water loss (TEWL). METHODS: TEWL is the standard measure of stratum corneumContinue Reading
  • R Alvarez-Román, A. Chandu Naik, Yogeshvar N Kalia, Hatem Fessi, Richard H. Guy
  • Chemistry, Medicine
  • European journal of pharmaceutics and…
  • 2004 (First Publication: 1 September 2004)
  • The use of skin as an alternative route for administering systemically active drugs has attracted considerable interest in recent years. However, the skin provides an excellent barrier, which limitsContinue Reading