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Gut microbiome contributes to impairment of immunity in pulmonary tuberculosis patients by alteration of butyrate and propionate producers
TLDR
The findings from this pilot study suggest that microbial dysbiosis may contribute to pathophysiology of TB by enhancing the anti-inflammatory milieu in the host. Expand
Microbial taxonomy in the era of OMICS: application of DNA sequences, computational tools and techniques
TLDR
A review of genomic approaches that can be included in the scheme of taxonomy of bacteria and archaea based on computational and in silico advances to boost the credibility of taxonomic classification in this genomic era is presented. Expand
Comparative Genomic Analysis Reveals Habitat-Specific Genes and Regulatory Hubs within the Genus Novosphingobium
TLDR
The results suggest that the phylogenetic relationships were mostly influenced by metabolic trait enrichment, which is possibly governed by the microenvironment of each microbe’s respective niche. Expand
Fictibacillus halophilus sp. nov., from a microbial mat of a hot spring atop the Himalayan Range.
TLDR
In spite of the high 16S rRNA gene sequence similarities, the DNA-DNA hybridization and gyr B gene sequencing results supported by physiological and biochemical tests demonstrated that strain AS8T is a representative of a novel species, for which the name Fictibacillus halophilus sp. Expand
Interplay of Human Gut Microbiome in Health and Wellness
TLDR
This work has reviewed dietary lifestyle and infectious diseases linked with the gut bacterial consortia to delineate the ecobiotic approaches towards their treatment and described the current therapeutic advancements of the pre- and probiotics derived from human microbiome studies to restore gut microbial homeostasis. Expand
Comparative genomic analysis of novel Acinetobacter symbionts: A combined systems biology and genomics approach
TLDR
This study used a network theory method for pathogenic and non-pathogenic Acinetobacter spp. Expand
Comparative Genomic Analysis of Rapidly Evolving SARS-CoV-2 Reveals Mosaic Pattern of Phylogeographical Distribution
TLDR
It is shown that there is no direct transmission pattern of the virus among neighboring countries, suggesting that its spread is a result of travel of infected humans to different countries, and the replicative machinery of SARS-CoV-2 is targeting interferon and the notch signaling pathway along with spliceosome machinery to evade host challenges. Expand
Corynebacteriumpollutisoli sp. nov., isolated from hexachlorocyclohexane-contaminated soil.
TLDR
Based on the results of DDH studies and the biochemical and physiological data, strain VDS11T represents a novel species of the genus Corynebacterium, for which the name CoryneBacterium pollutisoli sp. Expand
Comparative metagenomic analyses of a high-altitude Himalayan geothermal spring revealed temperature-constrained habitat-specific microbial community and metabolic dynamics
TLDR
This is a correlative study between three major habitats present in geothermal spring environment, i.e., water, sediment and microbial mats revealing greater phylogenetic and functional dispersion emphasizing changing habitat-specific dynamics with temperature. Expand
Comparative genomics of Sphingopyxis spp. unravelled functional attributes.
TLDR
Protein-Protein Interactome depicted that membrane proteins and stress response has close integration with core-proteins while aromatic compounds degradation and virulence ability formed a separate network, thus, these should be considered as strain specific attributes. Expand
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