Yo Tanaka

Learn More
In the process of neuronal wiring, axons derived from the same functional group typically extend together, resulting in fascicle formation. How these axons communicate with one another remains largely unknown. Here, we show that protocadherin-17 (Pcdh17) supports this group extension by recruiting actin polymerization regulators to interaxonal contact(More)
Lab-on-a-chip technology is promising for the miniaturization of chemistry, biochemistry, and/or biology researchers looking to exploit the advantages of a microspace. To manipulate fluid on a microchip, on-chip pumps are indispensable. To date, there have been several types of on-chip pumps including pneumatic, electroactive, and magnetically driven.(More)
In this study, we developed a method for fabricating a microfluidic device with integrated large-scale all-glass valves and constructed an actuator system to control each of the valves on the device. Such a microfluidic device has advantages that allow its use in various fields, including physical, chemical, and biochemical analyses and syntheses. However,(More)
Direct electric power generation using biological functions have become a research focus due to their low cost and cleanliness. Unlike major approaches using glucose fuels or microbial fuel cells (MFCs), we present a generation method with intrinsically high energy conversion efficiency and generation with arbitrary timing using living electric organs of(More)
The field of synthetic biology aims to understand the mechanisms of biological systems by designing and constructing artificial biological systems from molecular parts. One of the ultimate goals of the approach is to develop an artificial cell that is under the control of scientists. Although the creation of a bacterial cell controlled by a chemically(More)
Cone photopigments (opsins) are crucial elements of, and the first detection module in, color vision. Individual opsins have different wavelength sensitivity patterns, and the temporal and spatial expression patterns of opsins are unique and stringently regulated. Long and middle wavelength-sensitive (L/M) opsins are of the same phylogenetic type. Although(More)
long-term goal is to understand the molecular mechanisms, which coordi-nately regulate growth and differentiation of stem cells as well as differentiated cells with emphasis on intracellular signal transduction. For this purpose, we are using models ranging from iPS and various culture cells, zebrafish, mouse, to monkey. Based on our research background on(More)
  • 1