Learn More
PURPOSE To assess the prevalence of refractive error and visual impairment in school-age children in a metropolitan area of southern China. METHODS Random selection of geographically defined clusters was used to identify children 5 to 15 years of age in Guangzhou. Children in 22 clusters were enumerated through a door-to-door survey and examined in 71(More)
PURPOSE To assess the demographics and distribution of corneal astigmatism before cataract surgery in Chinese patients. SETTING State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China. DESIGN Clinic-based cross-sectional study. METHODS From July 2009 to May 2011, preoperative bilateral partial(More)
PURPOSE To assess the concentrations of vascular endothelial growth factor (VEGF) in aqueous humor in eyes with and without glaucoma. METHODS Concentrations of VEGF were measured using a sandwich ELISA kit in aqueous humor aspirates taken during anterior segment surgery from 87 patients, of whom 54 had glaucoma (27 primary open-angle glaucoma, 8(More)
The role of placental growth factor (PlGF) in modulation of tumor angiogenesis and tumor growth remains an enigma. Furthermore, anti-PlGF therapy in tumor angiogenesis and tumor growth remains controversial in preclinical tumor models. Here we show that in both human and mouse tumors, PlGF induced the formation of dilated and normalized vascular networks(More)
State-of-the-art near-duplicate image search systems mostly build on the bag-of-local features (BOF) representation. While favorable for simplicity and scalability, these systems have three shortcomings: 1) high time complexity of the local feature detection; 2) discriminability reduction of local descriptors due to BOF quantization; and 3) neglect of the(More)
To prevent pornography from spreading on the Internet effectively, we propose a novel method of adult image detection which combines bag-ofvisual-words (BoVW) based on region of interest (ROI) and color moments (CM). The goal of BoVW is to automatically mine the local patterns of adult contents, called visual words. The usual BoVW method clusters visual(More)
PURPOSE To compare the intraoperative and short-term postoperative outcomes of cataract surgery performed with torsional mode and conventional ultrasound mode using the Infiniti Vision System (Alcon Laboratories). SETTING Cataract Service, Zhongshan Ophthalmic Center, Sun-Yat-Sen University, Guangzhou, China. METHODS In this randomized comparative(More)
Diabetic retinopathy is characterized by pathological retinal neovascularization. Accumulating evidence has indicated that high levels of circulating endothelial progenitor cells (EPCs) are an important risk factor for neovascularization. Paradoxically, the reduction and dysfunction of circulating EPCs has been extensively reported in diabetic patients. We(More)
BACKGROUND Higher-order aberrations and contrast sensitivity were evaluated in patients who underwent phacoemulsification cataract extraction followed by implantation of aspherical, monofocal or multifocal intraocular lens (IOL) replacements. METHODS In this comparative trial, 124 patients with an average age of 66.8+/-5.2 years and their 124 eyes were(More)
PURPOSE To identify the mutation and the underlying mechanism of cataractogenesis in a five-generation autosomal dominant congenital lamellar cataract family. METHODS Nineteen mutation hot spots associated with autosomal dominant congenital cataract have been screened by PCR-based DNA sequencing. Recombinant wild-type and mutant human alphaB-crystallin(More)