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PURPOSE To assess the demographics and distribution of corneal astigmatism before cataract surgery in Chinese patients. SETTING State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China. DESIGN Clinic-based cross-sectional study. METHODS From July 2009 to May 2011, preoperative bilateral partial(More)
PURPOSE To assess the prevalence of refractive error and visual impairment in school-age children in a metropolitan area of southern China. METHODS Random selection of geographically defined clusters was used to identify children 5 to 15 years of age in Guangzhou. Children in 22 clusters were enumerated through a door-to-door survey and examined in 71(More)
PURPOSE To assess the concentrations of vascular endothelial growth factor (VEGF) in aqueous humor in eyes with and without glaucoma. METHODS Concentrations of VEGF were measured using a sandwich ELISA kit in aqueous humor aspirates taken during anterior segment surgery from 87 patients, of whom 54 had glaucoma (27 primary open-angle glaucoma, 8(More)
AIM To establish clone cells with different metastatic potential for the study of metastasis-related mechanisms. METHODS Cloning procedure was performed on parental hepatocellular carcinoma (HCC) cell line MHCC97, and biological characteristics of the target clones selected by in vivo screening were studied. RESULTS Two clones with high (MHCC97-H) and(More)
Diabetic retinopathy is characterized by pathological retinal neovascularization. Accumulating evidence has indicated that high levels of circulating endothelial progenitor cells (EPCs) are an important risk factor for neovascularization. Paradoxically, the reduction and dysfunction of circulating EPCs has been extensively reported in diabetic patients. We(More)
BACKGROUND Higher-order aberrations and contrast sensitivity were evaluated in patients who underwent phacoemulsification cataract extraction followed by implantation of aspherical, monofocal or multifocal intraocular lens (IOL) replacements. METHODS In this comparative trial, 124 patients with an average age of 66.8+/-5.2 years and their 124 eyes were(More)
PURPOSE To determine whether the overexpression of the proteasome catalytic beta5 subunit (PSMB5) can induce the expression of the catalytic subunits beta1 and beta2, enhance proteasome activity, and exert a cytoprotective effect in lens epithelial cells. METHODS Cells from the human lens epithelial cell line SRA01/04 (LECs) were stably transfected either(More)
Forkhead box O3 (FoxO3a) is a forkhead family transcription factor playing important roles in non-neuronal differentiation, metabolism, proliferation, and survival, but its role in neuronal differentiation remains unclear. In the present study, we investigated the role of FoxO3a in neuronal differentiation and its underlying mechanisms. Our results showed(More)
To take full advantage of the powerful computing capability of graphics processing units (GPU) to speed up local feature detection, we present a novel GPU-based scale invariant interest point detector, coined Harris-Hessian(H-H). H-H detects Harris points in low scale and refines their location and scale in higher scale-space with the determinant of Hessian(More)
To prevent pornography from spreading on the Internet effectively, we propose a novel method of adult image detection which combines bag-of-visual-words (BoVW) based on region of interest (ROI) and color moments (CM). The goal of BoVW is to automatically mine the local patterns of adult contents, called visual words. The usual BoVW method clusters visual(More)