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Immunotherapy of melanoma with the immune costimulatory monoclonal antibodies targeting CD137
Knowledge of how the immune system recognizes and attempts to control cancer growth and development has improved dramatically. The advent of immunotherapies for cancer has resulted in robust clinical… Expand
The expression change of OTUD3-PTEN signaling axis in glioma cells.
- Yizhen Liu, Xixun Du, Q. Zhao, Qian Jiao, H. Jiang
- Biology, Medicine
- Annals of translational medicine
- 1 April 2020
Background OTU domain-containing protein 3 (OTUD3), as a deubiquitinase (DUB) belonging to the ovarian tumor protease (OTU) family, has been reported to suppress tumor via OTUD3-PTEN signaling axis.… Expand
Urokinase-targeted recombinant bacterial protein toxins — a rationally designed and engineered anticancer agent for cancer therapy
Urokinase-targeted recombinant bacterial protein toxins are a sort of rationally designed and engineered anticancer recombinant fusion proteins representing a novel class of agents for cancer… Expand