A novel visible light promoted carbodifluoroalkylation of allylic alcohols is disclosed. A series of difluoro 1,5-dicarbonyl compounds were obtained through a tandem radical addition and 1,2-aryl migration process. Mechanistic analysis indicated that the 1,2-aryl rearrangement proceeded via a radical intermediate.
New coumarin-based chiral thiourea sensor 1 was found to be an enantioselective fluorescent chemosensor for N-Boc-protected proline. The chiral sensor shows lower background fluorescence, and higher fluorescence enhancement with 18 nm blue shifts. Job plot analysis result indicates that sensor 1 can form a 1 : 1 stoichiometric complex and it could be used… (More)
An Eu(III)-containing polymer can exhibit intense induced circularly polarized luminescence (CPL) in the presence of proline. In addition, the optical anisotropy factor (g(lum)) of the polymer for (5)D0 → (7)F1/(7)F2 transition was much higher than that of a single model molecule, which reveals the amplification effect of CPL arising from the conjugated… (More)
Chiral C₂-symmetric diamines have emerged as versatile auxiliaries or ligands in numerous asymmetric transformations. Chiral 2,2'-bispyrrolidine-based salan ligands were prepared and applied to the asymmetric aryl transfer to aldehydes with arylboronic acids as the source of transferable aryl groups. The corresponding diarylmethanols were obtained in high… (More)
Oxidative α-cyanation of tertiary amines is catalyzed by gold complexes with trimethylsilyl cyanide to afford the corresponding α-aminonitriles in the presence of tert-butyl hydroperoxide in good to excellent yields under acid-free conditions at room temperature.
As sensors with multiple chiral centers, salalen 1 and salan 2 composed of trans-cyclohexane-1,2-diamine (trans-DACH) and 1,1'-bi-2-naphthol (BINOL) units were designed and synthesized. Fluorescent recognition studies of resulting sensors towards mandelic acid (MA) reveal that salan 2a containing (R)-BINOL and (R,R)-DACH exhibits highly sensitive and… (More)
The direct reductive amination of aromatic aldehydes has been achieved with excellent isolated yields (89-96%) using readily accessible Ph(3)PAuCl/AgOTf catalyst along with ethyl Hantzsch ester as hydrogen source under mild reaction conditions.