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Crossing the blood‐brain barrier with nanoparticles
Abstract The blood‐brain barrier (BBB) is one of the most essential protection mechanisms in the central nervous system (CNS). It selectively allows individual molecules such as small lipid‐solubleExpand
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Carnitine Palmitoyltransferase-1b Deficiency Aggravates Pressure Overload–Induced Cardiac Hypertrophy Caused by Lipotoxicity
Background— Carnitine palmitoyltransferase-1 (CPT1) is a rate-limiting step of mitochondrial &bgr;-oxidation by controlling the mitochondrial uptake of long-chain acyl-CoAs. The muscle isoform,Expand
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Late Quaternary climatic and tectonic mechanisms driving river terrace development in an area of mountain uplift: A case study in the Langshan area, Inner Mongolia, northern China
Abstract The Langshan Range is located in the western Yin Mountain orogenic belts and the western Hetao fault-depression zone in Inner Mongolia, northern China. This area is on the northwesternExpand
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Recent development of carbon quantum dots regarding their optical properties, photoluminescence mechanism, and core structure.
Carbon quantum dots (CDs) are a relatively new class of carbon nanomaterials which have been studied very much in the last fifteen years to improve their already favorable properties. The opticalExpand
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Gel-like Carbon Dots: Characterization and their Potential Applications.
Highly photoluminescent gel-like carbon dots (G-CDs) were successfully synthesized for the first time by a rapid one-step solvothermal synthesis approach with citric acid and 1,2-ethylenediamine asExpand
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The Hearth and the Temple: Mapping Female Religiosity in Late Imperial China, 1550-1900
When the scholar and poet Lu Qi (b. 1614) married off his daughter, he gave her a didactic text authored by himself as a gift. Entitled Instructions for New Brides (Xinfu pu), the work contains aExpand
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Carbon dots: promising biomaterials for bone-specific imaging and drug delivery.
Bone-related diseases and dysfunctions are heavy burdens on our increasingly aged society. One important strategy to relieve this problem is through early detection and treatment of bone-relatedExpand
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Nanoparticle-mediated targeted drug delivery for breast cancer treatment.
Breast cancer (BC) is the most common malignancy in women worldwide, and one of the deadliest after lung cancer. Currently, standard methods for cancer therapy including BC are surgery followed byExpand
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Conditional PPARγ knockout from cardiomyocytes of adult mice impairs myocardial fatty acid utilization and cardiac function.
While the roles of PPARα and PPARδ (β) in transcriptional regulation of myocardial lipid metabolisms are well established, an essential role of PPARγ in regulating lipid metabolisms in the adultExpand
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Triple conjugated carbon dots as a nano-drug delivery model for glioblastoma brain tumors.
Most of the dual nano drug delivery systems fail to enter malignant brain tumors due to a lack of proper targeting systems and the size increase of the nanoparticles after drug conjugation.Expand
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