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- Publications
- Influence
Reciprocal Regulation of Metabolic Reprogramming and Epigenetic Modifications in Cancer
- X. Yu, Rui Ma, Yinsheng Wu, Yansheng Zhai, S. Li
- Biology, Medicine
- Front. Genet.
- 19 September 2018
Cancer cells reprogram their metabolism to meet their demands for survival and proliferation. The metabolic plasticity of tumor cells help them adjust to changes in the availability and utilization… Expand
MiR-26b-3p regulates osteoblast differentiation via targeting estrogen receptor α.
- Y. Lin, Lili Xiao, Yiyuan Zhang, P. Li, Yinsheng Wu, Yanping Lin
- Biology, Medicine
- Genomics
- 1 September 2019
BACKGROUND
Understanding of the molecular mechanisms of miRNAs involved in osteoblast differentiation is important for the treatment of bone-related diseases.
METHODS
MC3T3-E1 cells were induced to… Expand
Exogenous pyruvate represses histone gene expression and inhibits cancer cell proliferation via the NAMPT–NAD+–SIRT1 pathway
- Rui Ma, Yinsheng Wu, +8 authors S. Li
- Biology, Medicine
- Nucleic acids research
- 10 October 2019
Abstract Pyruvate is a glycolytic metabolite used for energy production and macromolecule biosynthesis. However, little is known about its functions in tumorigenesis. Here, we report that exogenous… Expand
Development of a Porcine Full-Thickness Burn Hypertrophic Scar Model and Investigation of the Effects of Shikonin on Hypertrophic Scar Remediation
- Xingwang Deng, Q. Chen, +8 authors Y. Xie
- Medicine
- Front. Pharmacol.
- 5 June 2018
Hypertrophic scars formed after burns remain a challenge in clinical practice. Development of effective scar therapies relies on validated animal models that mimic human hypertrophic scars. A… Expand
Ultrastructural change of the subchondral bone increases the severity of cartilage damage in osteoporotic osteoarthritis of the knee in rabbits.
Osteoporotic osteoarthritis is a phenotype of osteoarthritis (OA) manifested as fragile and osteoporotic subchondral bone. However, the ultrastructural features of subchondral bone in osteoporosis OA… Expand
MicroRNA-542-3p suppresses tumor cell proliferation via targeting Smad2 inhuman osteosarcoma
- Yinsheng Wu, Jiongming You, F. Li, F. Wang, Y. Wang
- Medicine
- Oncology letters
- 12 March 2018
Osteosarcoma (OS) is an aggressive malignant neoplasm that arises from primitive transformed cells of mesenchymal origin, and that exhibits osteoblastic differentiation and produces malignant… Expand
Effects of Ginsenosides Rg1 on Osteoblasts Cultured with Ti Particles
- Y. Lin, Yinsheng Wu, Jiacheng He, Yunmei Huang, Yanping Lin
- Medicine, Biology
- Biomolecules & therapeutics
- 1 January 2012
The aim of this study was to explore the role and effect of ginsenosides Rg1 on osteoblasts cultured with Ti particles. Osteoblasts from neonatal rats were cultured with particles and different doses… Expand
Japanese Encephalitis Virus Induces Apoptosis and Encephalitis by Activating the PERK Pathway
- Qianruo Wang, X. Xin, +13 authors L. Kong
- Biology, Medicine
- Journal of Virology
- 12 June 2019
Japanese encephalitis virus (JEV) infection triggers endoplasmic reticulum (ER) stress and neuron apoptosis. ER stress sensor protein kinase R-like endoplasmic reticulum kinase (PERK) has been… Expand
Glycolysis regulates gene expression by promoting the crosstalk between H3K4 trimethylation and H3K14 acetylation in Saccharomyces cerevisiae.
- Yinsheng Wu, Shihao Zhang, +7 authors Shan-Shan Li
- Biology, Medicine
- Journal of genetics and genomics = Yi chuan xue…
- 11 December 2019
Cells need to coordinate gene expression with their metabolic states to maintain cell homeostasis and growth. However, how cells transduce nutrient availability to appropriate gene expression… Expand
Membrane disruptive antimicrobial potential of NK-lysin from yellow catfish (Pelteobagrus fulvidraco).
- R. Zhu, Yinsheng Wu, +4 authors Xingguo Wang
- Biology, Medicine
- Fish & shellfish immunology
- 1 February 2020
NK-lysins, a type of broad-spectrum antimicrobial peptide (AMP), act as an essential effector of innate defense against microbial attack in higher vertebrates and so in fish. The present study… Expand