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Ontology matching produces correspondences between entities of two ontologies. The OMReasoner is unique in that it creates an extensible framework for combination of multiple individual matchers, and reasons about ontology matching by using external dictionary WordNet and description logic reasoner. It handles ontology matching in both literal and semantic(More)
The uracil DNA glycosylase superfamily consists of several distinct families. Family 2 mismatch-specific uracil DNA glycosylase (MUG) from Escherichia coli is known to exhibit glycosylase activity on three mismatched base pairs, T/U, G/U and C/U. Family 1 uracil N-glycosylase (UNG) from E. coli is an extremely efficient enzyme that can remove uracil from(More)
Enzymes in Uracil DNA glycosylase (UDG) superfamily are essential for the removal of uracil. Family 4 UDGa is a robust uracil DNA glycosylase that only acts on double-stranded and single-stranded uracil-containing DNA. Based on mutational, kinetic and modeling analyses, a catalytic mechanism involving leaving group stabilization by H155 in motif 2 and water(More)
Developing safety–critical embedded systems almost always includes a significant emphasis on risk analysis. Risk analysis is still a largely qualitative and manual method of analysis. In this paper, we propose a method for the quantitative analysis method of embedded systems based on the Architecture Analysis and Design Language (AADL) model. First, we(More)
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