Yingzhuang Chen

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Scutellaria baicalensis Georgi is a well-known medicinal plant widely used in China and other East Asian countries. High performance liquid chromatography combined with diode array detection and electrospray ion trap mass spectrometry was used to determine the flavonoid profile of S. baicalensis. Under the optimized experiment conditions, 32 flavonoids were(More)
A novel thiol-ene "click" strategy for the preparation of monolithic trypsin microreactor was proposed. The hybrid organic-inorganic monolithic capillary column with ene-functionality was fabricated by sol-gel process using tetramethoxysilane (TMOS) and γ-methacryloxypropyltrimethoxysilane (γ-MAPS) as precursors. The disulfide bonds of trypsin were reduced(More)
A novel sorbent for magnetic solid-phase extraction, 1,4,7,10-tetrabenzyl-1,4,7,10-tetraazacyclododecane (TBCD) modified magnetic nanoparticles, was synthesized in this work. The four benzyl groups of TBCD provide the Fe3O4-TBCD nanoparticles with strong adsorption capacity for polycyclic aromatic hydrocarbons (PAHs) due to their π-π stacking interaction,(More)
A novel (3-sulfopropyl methacrylate potassium)-silica hybrid monolithic column for CEC has been prepared by a simple one-pot approach based on efficient thiol-ene click chemistry. In this process, the polycondensation of hydrolyzed alkoxysilanes and in situ click reaction of vinyl groups on 3-sulfopropyl methacrylate potassium and thiol groups on the(More)
A cage-like silica nanoparticles-functionalized silica hybrid monolith for high performance capillary electrochromatography (CEC) has been prepared via "one-pot" process. In this process, the polycondensation of hydrolyzed alkoxysilanes and in situ reaction of mercaptopropyltrimethoxysilane (MPTS) with sodium 3-mercapto-1-propanesulfonate modified(More)
Triphenylamine (TPA)-functionalized magnetic microspheres (Fe(3)O(4)/SiO(2)/TPA) were prepared and applied as solid phase extraction (SPE) adsorbents for the analysis of polycyclic aromatic hydrocarbons (PAHs) in environmental samples in combination with high-performance liquid chromatography (HPLC). The magnetic solid-phase extraction (MSPE) conditions(More)
Ginsenosides have been widely conceded as having various biological activities and are considered to be the active ingredient of ginseng. Nowadays, preparative high-performance liquid chromatography is considered to be a highly efficient method for ginseng saponins purification and preparation. However, in the process of practical application, due to the(More)
A monolithic column with high affinity to fluorous compounds was prepared using a polyhedral oligomeric silsesquioxane (POSS) reagent as the cross-linker and pentadecafluorooctyl methacrylate (PDFOMA) as the functionality monomer. The pore properties and permeability could be tuned by the composition of the polymerization mixture. The characterization and(More)
One-pot synthesis of porous polymer monolith decorated with N-methylimidazolium in a capillary was described. The polymer matrix was synthesized by in situ copolymerization and quaterization of 3-chloro-2-hydroxylpropyl methacrylate (CHPMA), ethylene dimethacrylate (EDMA), and N-methylimidazole (N-MIz). The influencing factors including amount of(More)