Yingqing Feng

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The effects of atorvastatin on SDF-1α expression under acute myocardial infarction (AMI) are still unclear. Therefore, our present study is to investigate the roles and mechanisms of atorvastatin treatment on SDF-1α expression in rats with AMI. Male Sprague–Dawley rats were underwent permanent coronary artery ligation and randomly assigned into four groups(More)
OBJECTIVES The aim of this study is to evaluate the relationship of miR155 with office and ambulatory blood pressure (BP) parameters and left ventricular hypertrophy (LVH) in patients with hypertension and healthy controls. METHODS We assessed the expression level of the miR155 in 50 patients with essential hypertension and 30 healthy individuals. All(More)
Our objective was to evaluate the associations of the systolic and diastolic blood pressure night-to-day ratios (SBP-NDR and DBP-NDR) with composite atherosclerotic cardiovascular diseases (ASCVDs) comprising coronary heart disease (CHD) and ischemic stroke (IS) cases, respectively. The clinical conditions associated with SBP-NDR and DBP-NDR were also(More)
OBJECTIVE To evaluate the relationship between pulse pressure index (PPI) and carotid intima-media thickness (CIMT). METHOD Observational trial was design and 342 patients newly diagnosed as hypertension without anti-hypertensive therapy were enrolled. According to the cut-off value of CIMT, 342 participants were divided into normal (< 0.9mm) and(More)
OBJECTIVE To observe the long-term relationship between body mass index (BMI) and cardiovascular events in male elderly hypertensive patients. METHODS A total of 839 male elderly (>65 years old) hypertensive patients were included in this prospective study. Baseline data were obtained on January 2004 and participants were followed up yearly till January(More)
AIM The pressure study was carried out to evaluate the hypotheses that ambulatory blood pressure (ABP) is superior to clinic blood pressure for ischemic stroke and that ABP is important to refine risk stratification. PATIENTS AND METHODS A total of 889 hospitalized patients who had undergone ABP monitoring were enrolled. Baseline data were compared(More)
OBJECTIVE To characterize the clinical features of patients with cardiac amyloidosis (CA). METHODS Totally 42 patients with CA admitted to Guangdong General Hospital since 2008 were included and retrospectively analyzed in the present study. CA was confirmed by abdomen and endocardium biopsy examination. Clinical manifestations, electrocardiogram and(More)
OBJECTIVES The role of microRNAs (miRs,miRNAs) in the pathogenesis of cardiovascular diseases such as hypertension, as well as their diagnostic potential, has recently attracted much attention. However, target-organ damage (TOD) of hypertension remains a substantial challenge due to the lack of specific biomarkers. The present study was undertaken to(More)
OBJECTIVE To investigate the effects and mechanisms of amlodipine therapy on endothelium dysfunction induced by angiotensin-II (Ang-II) stimulation. METHODS Human umbilical vein endothelial cells (HUVECs) were used and divided into five groups: Blank control, Ang-II (10(-6 )mol/L), levorotatory amlodipine (5 × 10(-6 )mol/L) + Ang-II (10(-6 )mol/L),(More)
OBJECTIVE To investigate the clinical treatment effect of refractory hypertension accompanied with OSAHS by surgery on upper airway. METHOD Thirty-two patients were enrolled in our research. PSG and blood pressure were examined on preoperation and 6th month, 1 year, 2 year of postoperation. RESULT The AHI and the time of SaO2 < 90% were lower(More)