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Overexpression of RBBP6, Alone or Combined with Mutant TP53, Is Predictive of Poor Prognosis in Colon Cancer
TLDR
It is found that RBBP6 was overexpressed in colon tumorous tissues and was significantly associated with clinical stage, depth of tumor invasion, lymph node metastasis (LNM), distant metastasis, and histologic grade, and was an independent prognostic factor for overall survival and disease free survival (DFS). Expand
Zinc-α-2-Glycoprotein: A Candidate Biomarker for Colon Cancer Diagnosis in Chinese Population
TLDR
Zinc-α-2-glycoprotein (AZGP1) is a 41-kDa secreted glycoprotein, which has been detected in several malignancies, and its use as a diagnostic marker of colon cancer is hypothesized. Expand
Association of rs5764455 and rs6006473 polymorphisms in PARVB with liver damage of nonalcoholic fatty liver disease in Han Chinese population.
TLDR
Polymorphisms of rs5764455 and rs6006473 in PARVB gene in the Han Chinese population were found, and these polymorphisms were associated with the occurrence and progression of NAFLD. Expand
Elevated OCT1 participates in colon tumorigenesis and independently predicts poor prognoses of colorectal cancer patients
TLDR
The data indicate that OCT1 carries weight in colorectal carcinogenesis and functions as a novel prognostic indicator and a promising target of anti-cancer therapy for CRC. Expand
PAK6 increase chemoresistance and is a prognostic marker for stage II and III colon cancer patients undergoing 5-FU based chemotherapy
TLDR
It is demonstrated that PAK6 is an independent prognostic factor for adjuvant 5-FU-based chemotherapy in patients with stage II and stage III colon cancer and Animal experiments results in vivo are consistent with outcomes in vitro. Expand
Ubiquitin D is an independent prognostic marker for survival in stage IIB–IIC colon cancer patients treated with 5‐fluoruracil‐based adjuvant chemotherapy
TLDR
It is shown that ubiquitin D (UBD) can predict the prognosis of colon cancer; however, there are limited data on whether UBD is an independent prognostic factor for stage II patients treated with 5‐FU‐based adjuvant chemotherapy. Expand
Elevated kinesin family member 26B is a prognostic biomarker and a potential therapeutic target for colorectal cancer
TLDR
It is indicated that KIF26B plays an important role in colorectal carcinogenesis and functions as a novel prognostic indicator and a potential therapeutic target for CRC. Expand
Developmental pluripotency-associated 4: a novel predictor for prognosis and a potential therapeutic target for colon cancer
TLDR
The results indicate that Dppa4 might play an important role in colon cancer progression and function as a novel prognostic indicator and a potential therapeutic target. Expand
DDA1 promotes stage IIB–IIC colon cancer progression by activating NFκB/CSN2/GSK-3β signaling
TLDR
Results indicate that DDA1 promotes colon cancer progression through activation of NFκB/CSN2/GSK3β signaling, and may serve as a sensitive biomarker for tumor recurrence risk and prognosis in patients with stage IIB–IIC colon cancers. Expand
Expression of transmembrane protein 41A is associated with metastasis via the modulation of E‑cadherin in radically resected gastric cancer.
TLDR
The expression of TMEM41A was observed to be correlated with lymph node metastasis, distant metastasis and advanced tumor, node and metastasis stages, and may be considered as a novel therapeutic target for the treatment of GC‑associated metastasis. Expand
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