Yingfeng Zhou

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BACKGROUND AND OBJECTIVE DNA repair capacity is correlated with sensitivity of cancer cells toward platinum-based chemotherapy. The aim of this study was to investigate whether single nucleotide polymorphisms (SNPs) in polymorphisms of DNA repair gene ERCC1 (excision repair cross-complementation group 1) and XPD (ERCC2, excision repair cross-complementation(More)
Tetrandrine is known to exert antitumor effect, however, little is known about its effect on nasopharyngeal carcinoma cells. In this study, we tested tetrandrine-induced apoptosis and radiosensitivity in nasopharyngeal carcinoma cell line CNE and investigated the possible mechanisms. Using flow cytometry and DNA electrophoresis, we found that tetrandrine(More)
DNA repair capacity (DRC) is correlated with sensitivity of cancer cells toward platinum-based chemotherapy. We hypothesize that genetic polymorphisms in DNA repair gene XPA (xeroderma pigmentosum group A) and XPG (xeroderma pigmentosum group G) (ERCC5, excision repair cross-complementation group 5), which result in inter-individual differences in DNA(More)
Encapsulation of hydrophobic agents in polymer micelles can improve the water solubility of cargos, contributing to develop novel drugs. Quercetin (QU) is a hydrophobic agent with potential anticancer activity. In this work, we encapsulated QU into biodegradable monomethoxy poly(ethylene glycol)-poly(ε-caprolactone) (MPEG-PCL) micelles and tried to provide(More)
An automatic segmentation algorithm for touching rice grains images was proposed. Original gray image from rice inspection system was transformed into binary image and the edges of touching grains were extracted and de-noising was operated. This algorithm detected concave corner points of touching rice grains by a sector area and found corner point pairs by(More)
An adaptive learning rate Backpropagation Neural Network (BPNN) is proposed to image segmentation of rice disease spots. Rice blast is a common disease of rice and is tested in this paper. Firstly, the combination of different color feature parameters is selected as the input of the BPNN. Secondly, a BPNN with 5 input, 10 hidden neurons and 1 output is(More)
The effects of different Radix ranunculi ternati extracts on human gastric cancer BGC823 cells were investigated, different methods were used to extract the saponins and polysaccharides from Radix ranunculi ternati, and MTT assay and colony formation assay were used to observe the effects of saponins and polysaccharides from Radix ranunculi ternati on(More)
MicroRNAs (miRNAs) have been reported function as tumor suppressors or oncogenes. Ectopic expression of miRNA may lead to dysfunction of cell biological behaviors. MiR-451 is down-regulated and functions as a tumor suppressor mediated by different signal pathways. However, the expression pattern and the regulation mechanism of miR-451 remain to be(More)
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