Ji-yong Wang2
Yi-ping Li2
Lin Li2
2Ji-yong Wang
2Yi-ping Li
2Lin Li
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The low-density lipoprotein receptor-related proteins 5 and 6 (LRP5/6) are coreceptors for Frizzled and transmit signals from the plasma membrane to the cytosol. However, the mechanism for LRP5/6 signal transmission remains undefined. Here, we identify cytoplasmic activation/proliferation-associated protein 2 (Caprin-2) as a LRP5/6-binding protein. Our data(More)
  • Andrew E. Vaughan, Alexis N. Brumwell, Ying Xi, Jeffrey Gotts, Doug G. Brownfield, Barbara Treutlein +7 others
  • 2015
Broadly, tissue regeneration is achieved in two ways: by proliferation of common differentiated cells and/or by deployment of specialized stem/progenitor cells. Which of these pathways applies is both organ- and injury-specific. Current models in the lung posit that epithelial repair can be attributed to cells expressing mature lineage markers. By contrast,(More)
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