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TIP, a T-cell factor identified using high-throughput screening increases survival in a graft-versus-host disease model
A coordinated effort combining bioinformatic tools with high-throughput cell-based screening assays was implemented to identify novel factors involved in T-cell biology. We generated a unique libraryExpand
Palmitoylation of NOD1 and NOD2 is required for bacterial sensing
NODs require S-palmitoylation to signal The compartmentalization of proteins within the cell is essential for their function. The addition of lipid molecules redistributes proteins to the cellExpand
Polyploidy and new chromosome counts in Anaphalis (Asteraceae: Gnaphalieae) from the Qinghai‐Tibet Plateau of China
Abstract  Anaphalis is one of the largest genera of the Asian Gnaphalieae (Asteraceae) and is most diversified on the Qinghai‐Tibet Plateau. The chromosome numbers and karyomorphology of six speciesExpand
Chromosome numbers and polyploidy in Leontopodium (Asteraceae: Gnaphalieae) from the Qinghai-Tibet Plateau of S.W. China
Leontopodium R. Br. ex Cass. is the second largest genus within the Asian Gnaphalieae (Asteraceae) and is most diversified on the Qinghai-Tibet Plateau and its adjacent areas of SW China. TheExpand
Molecular Phylogeny of Ophiopogon (Asparagaceae) Inferred from Nuclear and Plastid DNA Sequences
Abstract The East and Southeast Asian genera Ophiopogon, Liriope, and Peliosanthes are classified in the tribe Ophiopogoneae (Asparagaceae). Phylogenetic relationships of this group were exploredExpand
Chromosome numbers, karyotypes, and polyploidy evolution of Anaphalis species (Asteraceae: Gnaphalieae) from the Hengduan Mountains, SW China
The chromosome numbers and karyomorphology of 32 accessions are examined, representing 12 species of Anaphalis DC. (Asteraceae) from the Hengduan Mountains of south-western China, which is mostExpand
Genome size variation among and within Ophiopogoneae species by flow cytometric analysis
Genome size variation in a taxonomic group reflects evolutionary processes. DNA contents of Ophiopogoneae (40 populations of 31 species) were estimated by flow cytometry. Ploidy levels of OphiopogonExpand
Molecular and morphologic identification of Pentatrichomonas hominis in swine.
A marasmic pig with watery diarrhea was identified to harbor the human-pathogenic protist Pentatrichomonas hominis by PCR and sequence analysis of three genetic loci (ITS1-5.8S rRNA-ITS2, 18S rRNA,Expand
Cholesterol Handling in Lysosomes and Beyond.
Lysosomes are of major importance for the regulation of cellular cholesterol homeostasis. Food-derived cholesterol and cholesterol esters contained within lipoproteins are delivered to lysosomes byExpand
Association of growth/differentiation factor 1 gene polymorphisms with the risk of congenital heart disease in the Chinese Han population
There is evidence suggesting that genetic variants of Nodal signaling may be associated with risk of congenital heart diseases (CHDs), in which several polymorphisms, such as Nodal rs1904589, haveExpand