Ying-Jung Chen

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Herein, we evaluated the anti-cancer effect and molecular mechanisms of a novel betulinic acid (BA) derivative, SYK023, by using two mouse models of lung cancer driven by KrasG12D or EGFRL858R. We found that SYK023 inhibits lung tumor proliferation, without side effects in vivo or cytotoxicity in primary lung cells in vitro. SYK023 triggered endoplasmic(More)
BACKGROUND/PURPOSE The present study prospectively investigated the incidence of and factors associated with hepatitis during antituberculous treatment in patients with tuberculosis and various underlying diseases. The results were compared with those of previously published studies. METHODS Patients treated with antituberculous agents were enrolled from(More)
This study examines 356 tertiary education students' entrepreneurial career intentions (ECI) and its influencing factors. The results show that students' labor Market information (LMI) has a significant direct effect on ECI, and employability self-efficacy (ESE) has a significant effect on ECI through LMI. The influence pattern and empirical data of ESE and(More)
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