Ying-Hua Chang

1Hsiao-Jen Chang
1Zachery R. Gregorich
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This study proposes a novel, efficient means of encoding genetic algorithms to solve the generalized plant allocation problem. The problem relates to allocating products across plants to minimize a total cost function. The proposed encoding method can reduce the search space of solutions more efficiently than the penalty encoding method does. The new(More)
The pathophysiology of heart failure (HF) is diverse, owing to multiple etiologies and aberrations in a number of cellular processes. Therefore, it is essential to understand how defects in the molecular pathways that mediate cellular responses to internal and external stressors function as a system to drive the HF phenotype. Mass spectrometry (MS)-based(More)
Tissue inhibitor metalloproteinase-1 (TIMP-1) is clinically associated with a poor prognosis for various cancers, but the roles of TIMP-1 in lung cancer metastasis are controversial. Our previous secretomic study revealed that TIMP-1 is highly abundant in high invasiveness cells of lung adenocarcinoma. In the current study, TIMP-1 abundances in primary lung(More)
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