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Crystal structure of Arabidopsis glutamyl-tRNA reductase in complex with its stimulator protein
Significance The glutamyl-tRNA reductase (GluTR)-catalyzed reduction of glutamyl-tRNA is the rate-limiting and a pivotal regulation step in the tetrapyrrole biosynthetic pathway. InExpand
The Non-canonical Tetratricopeptide Repeat (TPR) Domain of Fluorescent (FLU) Mediates Complex Formation with Glutamyl-tRNA Reductase*
Background: FLU negatively regulates glutamyl-tRNA reductase (GluTR) during chlorophyll biosynthesis. Results: The structures of the TPR domain of FLU in its uncomplexed form and the GluTR dimericExpand
Hemifacial spasm and trigeminal neuralgia in Chiari’s I malformation with hydrocephalus: Case report and literature review
Chiari's I malformation with hydrocephalus is commonly seen in clinical experience. Trigeminal neuralgia (TN) and hemifacial spasm (HFS) are most commonly related to vascular compression of the rootExpand
Does drug-target have a likeness?
OBJECTIVE The discovery of new targets that are sufficiently robust to yield marketable therapeutics is an enormous challenge. Conventional target identification approaches are disease-dependent,Expand
Do Institutions Matter? Estimating the Effects of Institutions on Economic Performance in China
This paper estimates the effects of institutions on economic performance with the cross-city data of China. We argue that China's ongoing reform belongs to the long historical transition fromExpand
Repair of left ventricular aneurysm during off-pump coronary artery bypass surgery.
BACKGROUND Acute myocardial infarction can result in left ventricular aneurysm, which may in turn cause congestive heart failure, ventricular arrhythmia and thromboembolic events. This studyExpand
Long-term benefits and feasibility of permanent left bundle branch pacing in patients with left bundle branch block
Objective To assess the long-term feasibility, safety and effectiveness of permanent left bundle branch pacing (LBBP) in patients with left bundle branch block (LBBB) . Methods Patients withExpand
Automatic Detection of Diabetic Retinopathy with Statistical Method and Bayesian Classifier
Liver metabonomics study on the protective effect of glycyrrhetinic acid against realgar-induced liver injury.
Glycyrrhetinic acid (GA) is the bioactive ingredient in Glycyrrhizae Radix et Rhizoma. Our previous study has reported that GA has protective effect on realgar-induced hepatotoxicity. However, theExpand