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Association of adiponectin and metabolic syndrome among patients taking atypical antipsychotics for schizophrenia: A cohort study
TLDR
Lower levels of adiponectin and weight gain after taking antipsychotic drugs are associated with higher risk of metabolic syndrome in patients taking atypical antipsychotics. Expand
Association analysis of the dopamine D3 receptor gene ser9gly and brain-derived neurotrophic factor gene val66met polymorphisms with antipsychotic-induced persistent tardive dyskinesia and clinical
TLDR
It is concluded that the BDNF val66met genetic polymorphism may exert its effect on the clinically phenotypic variability after TD has occurred and further replication studies with larger sample size and stringent definition for TD is necessary. Expand
Association Study of Adrenergic β3 Receptor (Trp64Arg) and G-Protein β3 Subunit Gene (C825T) Polymorphisms and Weight Change during Clozapine Treatment
TLDR
No statistically significant relationship was demonstrated for the investigated ADRB3 Trp64Arg and the GNB3 C825T polymorphisms in terms of BWC post-treatment, suggesting these two polymorphisms do not play a significant role in clozapine-induced BWC. Expand
C825T polymorphism in the human G protein beta3 subunit gene is associated with long-term clozapine treatment-induced body weight change in the Chinese population
TLDR
Findings confirm the importance of genetic factors in body weight change induced by long-term clozapine treatment in patients with schizophrenia, and indicate a role for the G protein beta3 subunit inBody weight regulation during long- term clozAPine treatment. Expand
Association Analysis of a Functional Catechol-O-Methyltransferase Gene Polymorphism in Schizophrenic Patients in Taiwan
TLDR
The results failed to show significant association between val158met polymorphism and schizophrenia, violence or suicide, however, the results showed a significant difference in age at disease onset among different genotypes. Expand
Association study of sertonin-6 receptor variant (C267T) with schizophrenia and aggressive behavior
The relative abundance of serotonin type 6 receptors (5-HT6) in some limbic regions and the high affinity of some antipsychotics to 5-HT6 receptors suggest that they might be involved in theExpand
Adiponectin as a potential biomarker for the metabolic syndrome in Chinese patients taking clozapine for schizophrenia.
TLDR
Independent of age and BMI, hypoadiponectinemia is a potential biomarker of the metabolic syndrome in patients taking clozapine for schizophrenia. Expand
Cytochrome P-450 2D6*10 C188T Polymorphism Is Associated with Antipsychotic-Induced Persistent Tardive Dyskinesia in Chinese Schizophrenic Patients
TLDR
It is concluded that the CYP2D6*10 C188T polymorphism may be associated with the susceptibility to the occurrence of TD induced by typical antipsychotics, especially in male patients, and may also be correlated with AIMS scores in TD patients. Expand
Association Analysis of the Genetic Variants of the N-Methyl D-Aspartate Receptor Subunit 2b (NR2b) and Treatment-Refractory Schizophrenia in the Chinese
TLDR
The results show that GRIN2B genetic variations were not a major risk factor for treatment-refractory schizophrenic patients, but may influence the effect of clozapine during treatment. Expand
Association Study of Angiotensin-Converting Enzyme Gene Polymorphism with Schizophrenia and Polydipsia
TLDR
A modest association was revealed between an insertion (I)/deletion (D) polymorphism of the ACE gene and polydipsia diagnosis for schizophrenic patients, and this association needs further replication as it may have implications for the pathogenesis and the treatment of polyDipsia for schizophrenia patients. Expand
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