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  • Jonathan M Maher, Matthew Z. Dieter, +10 authors Curtis D. Klaassen
  • Biology, Medicine
  • Hepatology
  • 2007 (First Publication: 1 November 2007)
  • UNLABELLED Multidrug resistance-associated proteins (Mrps) are adenosine triphosphate-dependent transporters that efflux chemicals out of cells. In the liver, Mrp2 transports bilirubin-glucuronide,Continue Reading
  • Ying Chen, Wendy N. Jefferson, Retha R. Newbold, Elizabeth Padilla-Banks, Melissa Elena Pepling
  • Biology, Medicine
  • Endocrinology
  • 2007 (First Publication: 1 August 2007)
  • In developing mouse ovaries, oocytes develop as clusters of cells called nests or germ cell cysts. Shortly after birth, oocyte nests dissociate and granulosa cells surround individual oocytes formingContinue Reading
  • Ying Chen, Murat S Durakoglugil, Xunde Xian, Joachim Herz
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences
  • 2010 (First Publication: 14 June 2010)
  • Apolipoprotein E (ApoE) genotype is a powerful genetic modifier of Alzheimer's disease (AD). The ApoE4 isoform significantly reduces the mean age-of-onset of dementia through unknown mechanisms.Continue Reading