Ying-Chao Zhang

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BACKGROUND & OBJECTIVE Atofloding (ATFU) is a new derivative of 5-fluorouracil. The phase I and II clinical study have been finished. The current study was a phase III clinical trail of ATFU. The aim of this study was to evaluate the efficacy, toxicity of ATFU combination chemotherapy and compare with ftorafur (FT-207) in patients with gastric cancer,(More)
Nowadays with the growing scale of computer network as well as the number of nodes, the traditional method of mobile agent based distributed intrusion detection system may cause severe problem of network congestion and time delay, for the data processing of all the nodes are converged to the central node which will lead to a mass data processing on it. In(More)
OBJECTIVES To evaluate the behavior of serum interleukin 10 (IL-10) in patients with acute pancreatitis and to explore the relationship between this cytokine and the severity of the disease. METHODS In 45 patients with acute pancreatitis, the serum concentrations of IL-10 was determined on days 1, 2, 3, 4, 5 after admission. Twelve healthy subjects were(More)
The soil contamination of heavy metals, from the areas of mine, highway, industrial area, agricultural land and so on, is nowadays a serious issue all over the world. The contamination of heavy metals in large agricultural area might lead to the decrease of products quality and economic value. Actually, the accumulation amount of heavy metals by crops is(More)
Analyzing methods of Fourier transform infrared spectroscopy (FTIR), scanning electron microscope (SEM), X-ray photoelectron spectroscopy (XPS), X-ray diffraction analysis (XRD) and X-ray fluorescence spectroscopy (XRF) were used to reveal the adsorption mechanism of Cr(VI) by low-cost adsorbent of rice husk ash. Results of FTIR showed that amide II band,(More)
Recommender System is one of the most important technologies in E-commerce, and the collaborative filtering algorithm is the most widely used technique .In this paper, we proposed an improved collaborative filtering algorithm based on bipartite network, degree of nodes and sort of nodes both have been taken into account. And we only need to calculate the(More)
In most of fuzzy querying systems, items in query conditions are assumed to carry equal importance, although it might not actually to be the case. Issues for expressing users’ preferences to query conditions are presented here. Relative importance between query items is introduced. Standard SQL is extended to express weighted fuzzy queries, such as(More)
BACKGROUND The aim of this study was to investigate the effect of a Lipofectamine2000 (Life2000) Transfection Reagent transfected psiRNA-STAT3 plasmid on 4T1 breast cancer cells. MATERIALS AND METHODS MTT was used to detect the cell proliferation of breast cancer 4T1 cells at different periods (0h, 6h, 8h, 10h); the cell cycle was assessed by flow(More)
In this paper, fourteen new L-proline derivatives were designed and synthesized, and their acetlcholinesterase (AChE) inhibitory activities were also investigated in vitro. New L-proline derivatives were prepared from substituted 2-bromo-1-acetophenones through four-step reaction; and their bioactivities as AChE inhibitors were measured by Ellman(More)
Soil contamination is regarded as one of the most serious issues to humanity all over the world. It is statistically believed that over one-fifth of the farmland, that is 20 million ha, is found to be contaminated by heavy metals in China. And the related issues, caused by soil contamination, of food safety, human health and eco-environmental quality(More)