Yin-Chien Ou

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Objective: To analyze the causes, clinical features a n d t r e a t m e n t o u t c o m e s i n p a t i e n t s w i t h n o n-obstructive azoospermia (NOA) and different severity of hypospermatogenesis (HS). Methods: This is a retrospective study from our reproductive clinic. Data of history, physical findings, serum hormone profiles and genetic studies(More)
Change in tumor size estimated using longitudinal tumor growth inhibition (TGI) modeling is an early predictive biomarker of clinical outcomes for multiple cancer types. We present the application of TGI modeling for subjects with multiple myeloma (MM). Longitudinal time course changes in M-protein data from relapsed and/or refractory MM subjects who(More)
countries were reviewed. Results: Two novel FLCN mutations were found in exon 9 and exon 7 respectively (c.946-947delAG and c.770-772delCCT). The cutaneous presentations were relatively rare in Asian countries. Conclusions: A definite diagnosis of BHD should only be made if a pathogenic FLCN germline mutation is detected. When cutaneous lesions are not(More)
Objective: Young men present as erectile dysfunction (ED) were usually thought to be related to psychiatric problems. Penile duplex Doppler ultrasonography (PDDU) is a minimally-invasive method for evaluating the penile hemodynamics in men with ED. To date, little is known about the findings of PDDU in men younger than 40 years. The aim of this study is to(More)
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